Edwards Morven S
Section of Infectious Diseases, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.
Semin Pediatr Infect Dis. 2006 Jul;17(3):149-52. doi: 10.1053/j.spid.2006.06.007.
The implementation of a culture screening-based approach to intrapartum antibiotic prophylaxis has been associated with substantial reduction in the incidence of early-onset group B streptococcal disease. Antibiotic prophylaxis is recognized as an interim strategy awaiting the licensure of a safe and effective conjugate vaccine for prevention of group B streptococcal infections in all susceptible populations. This article addresses concerns relating to antimicrobial resistance among group B streptococci that have arisen from use of intrapartum antibiotic prophylaxis and from increases in resistance in other gram-positive bacteria related genetically to group B streptococci.
采用基于培养物筛查的方法进行产时抗生素预防，已使早发型B族链球菌病的发病率大幅降低。抗生素预防被视为一种临时策略，等待一种安全有效的结合疫苗获得许可，用于预防所有易感人群中的B族链球菌感染。本文探讨了因产时抗生素预防的使用以及与B族链球菌在基因上相关的其他革兰氏阳性菌耐药性增加而引发的关于B族链球菌耐药性的问题。
