Ahoyo A-T, Baba-Moussa L, Makoutode M, Gbohoun A, Bossou R, Dramane K, Sanni A, Prévost G
Laboratoire de biochimie et biologie moléculaire, faculté des sciences et techniques, université d'Abomey-Calavi, 04 BP 0320 Cotonou, and Service de pédiatrie du centre hospitalier départemental du Zou et des Collines au Bénin.
Arch Pediatr. 2006 Nov;13(11):1391-6. doi: 10.1016/j.arcped.2006.07.004. Epub 2006 Aug 28.
Meticillin resistant Staphylococcus aureus (MRSA) is among the most important causes of nosocomial infections. It possesses a particular ability to spread in hospitals worldwide.
To analyze the proportion of MRSA among S. aureus isolated from specimen taken for diagnosis purposes. To make the medical staff aware of the problem of MRSA infections and to take a better care of patients.
During 3 months, a prospective study was carried out in the neonatal unit of centre hospitalier départemental du Zou et Collines in Benin. We identified newborn carriers of SA, particularly MRSA and factors associated with the carriage. Two hundred and ninety patients were admitted in the 3 divisions of the neonatal unit. From 195 specimens examined for diagnosis purposes 48 h after hospitalization, 112 patients were detected by nose swabbing. Concurrently, swabbing of environment was achieved.
Among patients'specimens, 141 isolations of S. aureus were observed. The proportion of MRSA was 36% amongst diagnostic specimens. MRSA represented 39% of the environment specimens. None of the isolated MRSA produces Panton Valentine leukocidin.
Our survey revealed a high level of MRSA among S. aureus isolated from diagnostic specimens. Consecutive to such findings and for decreasing nosocomial infection, an appropriate prevention program was installed, including intensive promotion of hands hygiene, correct sterilization and disinfection of materials and patients.
耐甲氧西林金黄色葡萄球菌(MRSA)是医院感染的最重要原因之一。它具有在全球医院中传播的特殊能力。
分析从用于诊断目的的标本中分离出的金黄色葡萄球菌中MRSA的比例。使医务人员意识到MRSA感染问题并更好地护理患者。
在3个月期间,在贝宁的祖省和科利内斯省中心医院新生儿科进行了一项前瞻性研究。我们确定了SA的新生儿携带者,特别是MRSA以及与携带相关的因素。新生儿科的3个科室收治了290名患者。在住院48小时后,从195份用于诊断目的的标本中,通过鼻拭子检测出112名患者。同时,对环境进行了拭子检测。
在患者标本中,观察到141株金黄色葡萄球菌分离株。诊断标本中MRSA的比例为36%。MRSA占环境标本的39%。分离出的MRSA均未产生杀白细胞素。
我们的调查显示,从诊断标本中分离出的金黄色葡萄球菌中MRSA水平较高。基于这些发现并为减少医院感染,实施了一项适当的预防计划,包括大力推广手部卫生、正确消毒和灭菌材料及患者。