Vasconcelos Olavo M, Prokhorenko Olga A, Kelley Kay F, Vo Alexander H, Olsen Cara H, Dalakas Marinos C, Halstead Lauro S, Jabbari Bahman, Campbell William W
Department of Neurology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
Arch Phys Med Rehabil. 2006 Sep;87(9):1213-7. doi: 10.1016/j.apmr.2006.06.009.
To examine the applicability and validity of traditional fatigue questionnaires in postpoliomyelitis syndrome (PPS) patients with disabling fatigue.
Cross-sectional study. PPS and disabling fatigue were ascertained according to published criteria. Descriptiveness was determined using the McNemar test, and interscale z-score agreement was estimated with Pearson's coefficients.
PPS clinic.
Fifty-six survivors of poliomyelitis: 39 met criteria for PPS, 25 of whom met criteria for disabling fatigue.
Not applicable.
The Fatigue Severity Scale (FSS), visual analog scale (VAS) for fatigue, and Fatigue Impact Scale (FIS).
Twenty-four patients scored 50% or higher on the scale range for FSS, compared with 19 patients for VAS for fatigue (P=.042), and 7 patients for FIS (P<.001). Scores for patients with disabling fatigue averaged 81.5%, 62%, and 40.9% of the scale range for FSS, VAS for fatigue, and FIS, respectively. Agreement was moderate between the FSS and VAS for fatigue (r=.45, P=.02), but low between FSS and FIS (r=.29, P=.15), and FIS and VAS for fatigue (r=.20, P=.33). Two sample t tests showed significant differences between those with disabling fatigue and those without, based on FSS scores (t=3.8, P<.001), but not for VAS for fatigue or FIS scores.
FSS was the most descriptive of the instruments tested. Scores generated by the scales were not interchangeable. Of the 3 scales, FFS seemed to be the most informative for the clinical assessment of fatigue in patients with PPS.
探讨传统疲劳问卷在患有致残性疲劳的小儿麻痹后遗症(PPS)患者中的适用性和有效性。
横断面研究。根据已发表的标准确定PPS和致残性疲劳。使用麦克尼马尔检验确定描述性,并使用皮尔逊系数估计量表间的z分数一致性。
PPS诊所。
56名小儿麻痹症幸存者:39名符合PPS标准,其中25名符合致残性疲劳标准。
不适用。
疲劳严重程度量表(FSS)、疲劳视觉模拟量表(VAS)和疲劳影响量表(FIS)。
24名患者在FSS量表范围内得分达到或高于50%,相比之下,疲劳VAS量表有19名患者(P = 0.042),FIS量表有7名患者(P < 0.001)。患有致残性疲劳的患者在FSS、疲劳VAS和FIS量表范围内的得分分别平均为81.5%、62%和40.9%。FSS与疲劳VAS之间的一致性为中等(r = 0.45,P = 0.02),但FSS与FIS之间较低(r = 0.29,P = 0.15),FIS与疲劳VAS之间也较低(r = 0.20,P = 0.33)。两样本t检验显示,基于FSS得分,患有致残性疲劳者与未患有者之间存在显著差异(t = 3.8,P < 0.001),但疲劳VAS或FIS得分无显著差异。
FSS是所测试工具中描述性最强的。各量表产生的分数不可互换。在这3个量表中,FFS似乎对PPS患者疲劳的临床评估最具信息量。