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意大利吸烟法规对急性心肌梗死住院率的短期影响。

Short-term effects of Italian smoking regulation on rates of hospital admission for acute myocardial infarction.

作者信息

Barone-Adesi Francesco, Vizzini Loredana, Merletti Franco, Richiardi Lorenzo

机构信息

Cancer Epidemiology Unit, CeRMS and Center for Oncologic Prevention Piemonte, University of Turin, Via Santena 7, 10126 Turin, Italy.

出版信息

Eur Heart J. 2006 Oct;27(20):2468-72. doi: 10.1093/eurheartj/ehl201. Epub 2006 Aug 29.

DOI:10.1093/eurheartj/ehl201
PMID:16940340
Abstract

AIMS

We used the hospital discharge records of Piedmont region (northern Italy) to evaluate whether a national law banning smoking in public resulted in a short-term reduction in hospital admissions for acute myocardial infarction (AMI).

METHODS AND RESULTS

Rates of admission for AMI before the ban (October-December 2004) and during the ban (February-June 2005) were analysed. Each period was compared with the corresponding period 12 months before. Among persons aged under 60, the number of admissions for AMI decreased significantly after the introduction of the ban: from 922 cases in February-June 2004 to 832 cases in February-June 2005 (sex- and age-adjusted rate ratio, 0.89; 95% confidence interval, 0.81-0.98). No decrease was seen before the ban. No effect was found among persons aged at least 60. We estimated that the observed reduction in active smoking after the introduction of the ban could account for a 0.7% decrease in admissions for AMI during the study period, suggesting that most of the observed effect (11%) might be due to the reduction of passive smoking.

CONCLUSION

Our study, based on a population of about 4 million inhabitants, suggests that smoke-free policies may result in a short-term reduction in admissions for AMI.

摘要

目的

我们利用意大利北部皮埃蒙特地区的医院出院记录,评估一项禁止在公共场所吸烟的国家法律是否能使急性心肌梗死(AMI)的住院人数在短期内减少。

方法与结果

分析了禁令实施前(2004年10月至12月)和禁令实施期间(2005年2月至6月)AMI的入院率。将每个时期与12个月前的相应时期进行比较。在60岁以下人群中,禁令实施后AMI的入院人数显著下降:从2004年2月至6月的922例降至2005年2月至6月的832例(性别和年龄调整后的率比为0.89;95%置信区间为0.81-0.98)。禁令实施前未见下降。在60岁及以上人群中未发现影响。我们估计,禁令实施后观察到的主动吸烟减少可使研究期间AMI的入院人数减少0.7%,这表明观察到的大部分影响(11%)可能是由于被动吸烟的减少。

结论

我们基于约400万居民的研究表明,无烟政策可能会使AMI的住院人数在短期内减少。

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