Zutshi M, Hull T L, Trzcinski R, Arvelakis A, Xu M
Department of Colorectal Surgery, Cleveland Clinic Foundation, Desk A-30, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
Int J Colorectal Dis. 2007 Mar;22(3):265-9. doi: 10.1007/s00384-006-0189-3. Epub 2006 Aug 31.
Long-term outcome after surgery for slow transit constipation is conflicting. The aim of this study was to assess long-term quality of life after surgery.
The medical records of all patients undergoing colectomy with ileorectal anastomosis between 1983 and 1998 were evaluated. Preoperative, operative, and postoperative details were recorded. A survey was conducted to evaluate current symptoms and health. Quality of life was assessed using the short-form (SF)-36 survey.
Sixty-nine (2 male) patients were identified. Five were deceased. Mean age at surgery was 38.6 years (range, 19.7-78.8 years). Median follow-up after surgery was 10.8 years (range, 5.1-18.6 years). Forty-one percent had a family history of constipation. Eleven (16%) had an ileus postoperatively, which responded to medical therapy. One patient had a leak that required temporary diversion. Long-term complications occurred in 32 (46%) patients, which included hernias (3 patients; 4%), pelvic abscess (1 patient; 1.5%), rectal pain (1 patient; 1.5%), small-bowel obstruction (14 patients; 20%, with eight requiring surgery), diarrhea (5 patients; 7%), incontinence (1 patient, 1.5%), and persistent constipation (6 patients; 9%). Fifty-five percent (35/64) responded to a questionnaire. Overall, 25 of 35 (77% of the respondents) stated that surgery was beneficial. Sixty-four percent of patients have semisolid stools, 35% have liquid stools, and 4% reported hard stool. Results of the SF-36 showed the physical component score was comparable with healthy individuals. However, the mental component score was low especially in the areas of vitality (median, 45) and social functioning (median, 37).
Surgery for constipation is not perfect, and preoperative symptoms may persist after surgery. When assessing long-term quality of life, the mental component of the SF-36 was low compared with the general population, and the physical component was similar. Moreover, because 77% report long-term improvement, surgery is beneficial for appropriate patients.
慢传输型便秘手术后的长期疗效存在争议。本研究旨在评估手术后的长期生活质量。
对1983年至1998年间所有接受结肠切除术并进行回肠直肠吻合术的患者的病历进行评估。记录术前、手术中和术后的详细情况。进行一项调查以评估当前症状和健康状况。使用简短健康调查问卷(SF-36)评估生活质量。
共确定69例患者(2例男性)。5例患者死亡。手术时的平均年龄为38.6岁(范围为19.7 - 78.8岁)。术后中位随访时间为10.8年(范围为5.1 - 18.6年)。41%的患者有便秘家族史。11例(16%)患者术后发生肠梗阻,经药物治疗后缓解。1例患者出现吻合口漏,需要临时改道。32例(46%)患者发生长期并发症,包括疝气(3例;4%)、盆腔脓肿(1例;1.5%)、直肠疼痛(1例;1.5%)、小肠梗阻(14例;20%,其中8例需要手术)、腹泻(5例;7%)、大便失禁(1例,1.5%)和持续性便秘(6例;9%)。64例患者中有55%(35/64)回复了问卷。总体而言,35例中的25例(占受访者的77%)表示手术有益。64%的患者大便呈半固体状,35%的患者大便呈液体状,4%的患者报告大便干结。SF-36的结果显示,身体成分得分与健康个体相当。然而,心理成分得分较低,尤其是在活力(中位数为45)和社会功能(中位数为37)方面。
便秘手术并不完美,术前症状在术后可能持续存在。在评估长期生活质量时,与普通人群相比SF-36的心理成分得分较低,而身体成分得分相似。此外,由于77%的患者报告长期病情改善,手术对合适的患者有益。