Nylund G, Oresland T, Fasth S, Nordgren S
Colorectal Unit, Sahlgrenska Universitetssjukhuset, University of Göteborg, S-416 85 Göteborg, Sweden.
Colorectal Dis. 2001 Jul;3(4):253-8. doi: 10.1046/j.1463-1318.2001.00249.x.
The specific aim of the investigation was to assess the long-term results of subtotal colectomy with ileorectal anastomosis in patients with severe idiopathic constipation.
40 patients with severe idiopathic constipation were operated on between 1981 and 1993. Patients were accepted for a colectomy and an ileo-rectal anatomosis after a thorough gastro-intestinal investigation. Pre-operative bowel frequency was less than 2 movements per week, and slow transit was documented. Postoperative complications occurred in eight patients. Early re-operation was performed in 2 patients for small bowel obstruction.
Mean follow-up was 11 (range 5-16) years. The defaecation frequency at follow-up was 3.0 +/- 1.9 per day. Twenty-nine patients stated that they were satisfied and 11 were dissatisfied with the procedure. The outcome did not correlate with observed signs of outlet obstruction, blunted rectal sensation or presence of a psychiatric diagnosis. At 5-16 years after the procedure 33 patients still retain the ileo-rectal anastomosis. Seven patients have had further procedures: Five patients have an ileo-anal pouch, one has a continent ileostomy and one has a conventional ileostomy. Small bowel obstruction was encountered in 17 patients, in 10 of these surgical treatment was necessary.
It is concluded that colectomy and ileorectal anastomosis for the treatment of severe idiopathic constipation causes an increase in the number of bowel motions, but is deemed successful only by 3 out of 4 patients. Secondary morbidity is considerable.
本研究的具体目的是评估重症特发性便秘患者行结肠次全切除回直肠吻合术的长期疗效。
1981年至1993年间,对40例重症特发性便秘患者进行了手术。在进行全面的胃肠道检查后,这些患者接受了结肠切除术和回直肠吻合术。术前排便频率低于每周2次,且有结肠传输缓慢的记录。8例患者出现术后并发症。2例患者因小肠梗阻接受了早期再次手术。
平均随访时间为11年(范围5 - 16年)。随访时排便频率为每天3.0±1.9次。29例患者表示对手术满意,11例不满意。手术结果与观察到的出口梗阻体征、直肠感觉迟钝或精神疾病诊断无关。术后5 - 16年,33例患者仍保留回直肠吻合术。7例患者接受了进一步手术:5例患者行回肠肛管袋术,1例患者行可控性回肠造口术,1例患者行传统回肠造口术。17例患者发生小肠梗阻,其中10例需要手术治疗。
结肠次全切除回直肠吻合术治疗重症特发性便秘可增加排便次数,但仅四分之三的患者认为手术成功。继发性发病率较高。