Hosoya Y, Taguchi T, Tay F R
Nagasaki University Graduate School of Biomedical Sciences, Course of Medical and Dental Sciences, Department of Developmental and Reconstractive Medicine, Division of Pediatric Dentistry, 1-7-1, Sakamoto, Nagasaki 852-8588, Japan.
J Dent. 2007 Feb;35(2):137-43. doi: 10.1016/j.jdent.2006.06.004. Epub 2006 Sep 1.
This study evaluated the clinical efficacy of a new caries detecting dye using a laser fluorescence device (DIAGNOdent).
Primary and permanent teeth with dentin caries were stained with Caries Check (CC), containing 1% acid red in polypropylene glycol (MW=300) or Caries Detector (CD), containing 1% acid red in propylene glycol (MW=76). Primary-CC, primary-CD, permanent-CC and permanent-CD groups were prepared. In the CC groups, stained dentin was completely removed. In the CD groups, pink-stained dentin was retained according to the manufacturers' instructions. Cavities before and after caries removal were measured with the DIAGNOdent. Data were analyzed using ANOVA and Fisher's PLSD multiple comparison test at alpha=0.05. Regression analyses were performed between DIAGNOdent readings and scores obtained from the clinical parameters.
For all groups, there were no significant differences in the DIAGNOdent readings before treatment. The DIAGNOdent readings after caries removal were: primary-CC (16.0+/-17.6), primary-CD (9.6+/-5.2), permanent-CC (11.0+/-7.0) and permanent-CD (7.1+/-3.8). Significant differences were identified between the permanent-CC and primary-CD, and permanent-CC and permanent-CD subgroups but not for the primary subgroups. Correlation coefficients between DIAGNOdent readings and clinical parameters were low.
When dentin stained with Caries Check was completely removed, the DIAGNOdent readings were higher than those recorded when palely-stained pink dentin was retained with the Caries Detector, with significant difference observed for the permanent teeth. Caries Check may be used clinically to avoid excessive removal of caries-affected or sound dentin in permanent teeth but not in primary teeth.
本研究使用激光荧光装置（DIAGNOdent）评估一种新型龋齿检测染料的临床疗效。
用含有1%酸性红的聚丙二醇（分子量=300）的龋齿检查染料（CC）或含有1%酸性红的丙二醇（分子量=76）的龋齿检测染料（CD）对患有牙本质龋的乳牙和恒牙进行染色。制备乳牙-CC组、乳牙-CD组、恒牙-CC组和恒牙-CD组。在CC组中，将染色的牙本质完全去除。在CD组中，按照制造商的说明保留粉红色染色的牙本质。使用DIAGNOdent测量去龋前后的龋洞。数据采用方差分析和Fisher最小显著差异多重比较检验进行分析，α=0.05。对DIAGNOdent读数与临床参数获得的分数进行回归分析。
对于所有组，治疗前DIAGNOdent读数无显著差异。去龋后的DIAGNOdent读数分别为：乳牙-CC组（16.0±17.6）、乳牙-CD组（9.6±5.2）、恒牙-CC组（11.0±7.0）和恒牙-CD组（7.1±3.8）。在恒牙-CC组与乳牙-CD组以及恒牙-CC组与恒牙-CD组亚组之间发现了显著差异，但在乳牙亚组中未发现。DIAGNOdent读数与临床参数之间的相关系数较低。
当用龋齿检查染料染色的牙本质被完全去除时，DIAGNOdent读数高于使用龋齿检测染料保留浅粉红色染色牙本质时记录的读数，恒牙中观察到显著差异。龋齿检查染料可在临床上用于避免恒牙中过度去除受龋影响或健康的牙本质，但不适用于乳牙。
