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也门普通牙医对抗菌药物处方的了解情况。

Knowledge of prescribing antimicrobials among Yemeni general dentists.

作者信息

Al-Haroni Mohammed, Skaug Nils

机构信息

Department of Oral Sciences-Oral Microbiology, Faculty of Dentistry, University of Bergen, Norway.

出版信息

Acta Odontol Scand. 2006 Oct;64(5):274-80. doi: 10.1080/00016350600672829.

Abstract

OBJECTIVE

Overuse of antimicrobial agents is closely related to an increase in bacterial resistance. A sound knowledge of appropriate prescribing of antimicrobials among health professionals is thus critical in combating the resistance. The objectives of this study were to assess the rationale for and patterns of antimicrobial prescriptions by general dental practitioners in Yemen.

MATERIAL AND METHODS

A questionnaire containing 65 closed questions was used for this cross-sectional study and distributed to 280 dentists in the three major governorates in Yemen. The anonymously completed questionnaires sought answers to demographic questions and to questions on the therapeutic and prophylactic use of antimicrobial agents in dentistry. Correct and incorrect answers were defined according to information available in the current authoritative literature. Each correct answer was given a score of 1 while an incorrect answer scored 0. Thus, the total score had an attainable range from 0 to 65. Frequencies, means, and associations were assessed statistically.

RESULTS

Out of 181 collected forms (response rate 64.6%), 150 were appropriately completed and used for data analyses. Penicillins were the most frequently prescribed drugs (72%), followed by spiramycin (10%). It was found that up to 84% of practitioners were likely to prescribe an antimicrobial agent when there was no clinical indication for such a medication. Many respondents (70%) would consider antibiotics for at least one of the given non-clinical factors.

CONCLUSIONS

The results suggest that dental practitioners in Yemen lack uniformity in the rationale for appropriate prescribing of antimicrobials to their patients. Consequently, to reduce overuse, there is an urgent need for the dental community in the country to be informed about evidence-based guidelines and the appropriate use of antimicrobial agents in clinical dental practice.

摘要

目的

抗菌药物的过度使用与细菌耐药性增加密切相关。因此,卫生专业人员对抗菌药物合理处方的充分了解对于对抗耐药性至关重要。本研究的目的是评估也门普通牙科医生抗菌药物处方的依据和模式。

材料与方法

本横断面研究使用了一份包含65个封闭式问题的问卷,并分发给也门三个主要省份的280名牙医。匿名填写的问卷寻求有关人口统计学问题以及牙科中抗菌药物治疗和预防性使用问题的答案。根据当前权威文献中的可用信息定义正确和错误答案。每个正确答案得1分,错误答案得0分。因此,总分的可达到范围为0至65分。对频率、均值和关联性进行统计学评估。

结果

在收集的181份表格中(回复率64.6%),150份填写恰当并用于数据分析。青霉素是最常处方的药物(72%),其次是螺旋霉素(10%)。结果发现,高达84%的从业者在没有临床用药指征时可能会开具抗菌药物。许多受访者(70%)会因至少一个给定的非临床因素而考虑使用抗生素。

结论

结果表明,也门的牙科医生在为患者合理开具抗菌药物的依据方面缺乏一致性。因此,为减少过度使用,该国牙科界迫切需要了解循证指南以及抗菌药物在临床牙科实践中的合理使用。

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