桔梗根中的新型A环内酯三萜皂苷。

New A-ring lactone triterpenoid saponins from the roots of Platycodon grandiflorum.

作者信息

Fu Wen-Wei, Shimizu Noriko, Takeda Tadahiro, Dou De-Qiang, Chen Baohui, Pei Yue-Hu, Chen Ying-Jie

机构信息

Shenyang Pharmaceutical University, School of Traditional Chinese Material, 103 Wenhua Road, Shenhe District, Shenuang 110016, China.

出版信息

Chem Pharm Bull (Tokyo). 2006 Sep;54(9):1285-7. doi: 10.1248/cpb.54.1285.

DOI:10.1248/cpb.54.1285

PMID:16946536

Abstract

Three new A-ring lactone triterpenoid saponins, platycoside M-1 [3-O-beta-D-glucopyranosyl platycogenic acid A lactone], platycoside M-2 [3-O-beta-D-glucopyranosyl platycogenic acid A lactone 28-O-alpha-L-rhamnopyranosyl-(1-->2)-alpha-L-arabinopyranoside], and platycoside M-3 [3-O-beta-D-glucopyranosyl platycogenic acid A lactone 28-O-beta-D-xylopyranosyl-(1-->4)-alpha-L-rhamnopyranosyl-(1-->2)-alpha-L-arabinopyranoside], were isolated from the roots of Platycodon grandiflorum A. DC. Their chemical structures were elucidated on the basis of their spectral data and chemical evidence.

摘要

从桔梗（Platycodon grandiflorum A. DC.）根部分离得到三种新的A环内酯三萜皂苷，分别为桔梗皂苷M-1 [3-O-β-D-吡喃葡萄糖基桔梗酸A内酯]、桔梗皂苷M-2 [3-O-β-D-吡喃葡萄糖基桔梗酸A内酯28-O-α-L-鼠李吡喃糖基-(1→2)-α-L-阿拉伯吡喃糖苷]和桔梗皂苷M-3 [3-O-β-D-吡喃葡萄糖基桔梗酸A内酯28-O-β-D-木吡喃糖基-(1→4)-α-L-鼠李吡喃糖基-(1→2)-α-L-阿拉伯吡喃糖苷]。基于它们的光谱数据和化学证据阐明了其化学结构。