Asanin Milika, Vasiljevic Zorana, Matic Mihailo, Vujisic-Tesic Bosiljka, Arandjelovic Aleksandra, Marinkovic Jelena, Ostojic Miodrag
University Institute for Cardiovascular Disease, Clinical Center of Serbia, Emergency Center, Belgrade, Serbia and Montenegro.
Cardiology. 2007;107(3):197-202. doi: 10.1159/000095417. Epub 2006 Aug 12.
The duration of new-onset atrial fibrillation (AF) following the acute myocardial infarction (AMI) was evaluated as well as its relation to in-hospital and 7-year mortality.
A total of 320 consecutive patients with AF following AMI were examined and patients with AF <7 h (n = 141) were compared to those with AF > or =7 h in duration (n = 179). Receiver Operating Characteristic analysis was performed to identify the most useful AF duration cut-off level for the prediction of poor outcome. Patients with longer AF duration were older and had more advanced heart failure than patients with short arrhythmia duration. Patients with longer AF duration had worse outcome, including higher in-hospital (22.3 vs. 12.8%) and 7-year (67.4 vs. 34.4%) mortality. After multivariate adjustment, longer AF duration remained an independent predictor of long-term mortality (relative risk = 2.04, 95% confidence interval = 1.39-2.99, p = 0.0002).
New-onset AF > or =7 h in duration following the AMI independently predicts long-term mortality.
评估急性心肌梗死（AMI）后新发房颤（AF）的持续时间及其与住院期间和7年死亡率的关系。
共检查了320例连续的AMI后发生AF的患者，并将AF持续时间<7小时的患者（n = 141）与AF持续时间≥7小时的患者（n = 179）进行比较。进行了受试者工作特征分析，以确定预测不良结局最有用的AF持续时间截断水平。AF持续时间较长的患者比心律失常持续时间短的患者年龄更大，心力衰竭更严重。AF持续时间较长的患者结局更差，包括更高的住院期间死亡率（22.3%对12.8%）和7年死亡率（67.4%对34.4%）。多变量调整后，较长的AF持续时间仍然是长期死亡率的独立预测因素（相对风险=2.04，95%置信区间=1.39 - 2.99，p = 0.0002）。
AMI后持续时间≥7小时的新发AF独立预测长期死亡率。
