Naldöken S, Ercan M T, Bekdik C F
Department of Nuclear Medicine, Hacettepe University Medical Faculty, Ankara, Turkey.
Eur J Nucl Med. 1990;16(3):143-7. doi: 10.1007/BF01146852.
99mTc-Dextran (99mTc-D) was evaluated as an iliopelvic lymphoscintigraphic agent in 49 patients with malignant lymphoma and the results were compared with ultrasound (US), lymphangiography (LA) and CT where available. Scintigrams were obtained by a gamma camera at 2 h postinjection and evaluated by comparing opposite sides. In 29 of 49 patients, normal lymphoscintigrams of excellent quality, deliniating the iliopelvic and paraaortic lymph nodes bilaterally were obtained. In 20 patients lymphoscintigraphy (LS) was positive. US was performed in 46 patients, 20 had positive and 26 negative findings. There was one false positive and one false negative in LS compared to US. Ten patients had LA and 3 had CT. These results were in complete agreement with LS. There was also a positive correlation between the clinical stages and the results of LS. This study showed that 99mTc-D is an excellent radiopharmaceutical for the visualization of the lymph system with high correlation with other imaging modalities.
对49例恶性淋巴瘤患者评估了99m锝-右旋糖酐（99mTc-D）作为髂盆腔淋巴闪烁造影剂的效果，并将结果与超声（US）、淋巴管造影（LA）以及（如有条件）CT进行比较。在注射后2小时用γ相机获取闪烁扫描图，并通过双侧对比进行评估。49例患者中有29例获得了质量极佳的正常淋巴闪烁扫描图，双侧清晰显示了髂盆腔和腹主动脉旁淋巴结。20例患者淋巴闪烁造影（LS）呈阳性。46例患者进行了超声检查，20例结果阳性，26例结果阴性。与超声相比，淋巴闪烁造影有1例假阳性和1例假阴性。10例患者进行了淋巴管造影，3例进行了CT检查。这些结果与淋巴闪烁造影完全一致。临床分期与淋巴闪烁造影结果之间也存在正相关。本研究表明，99mTc-D是一种用于淋巴系统显像的优秀放射性药物，与其他成像方式高度相关。
