Castro Therezita Peixoto Patury Galvão, Bussoloti Filho Ivo
Department of Otorhinolaryngol, FCMSCSP, UNCISAL, UFAL, Brazil.
Braz J Otorhinolaryngol. 2006 Mar-Apr;72(2):272-82. doi: 10.1016/s1808-8694(15)30068-9.
The prevalence of human papillomavirus (HPV) in the oral cavity and oropharynx has not yet been as well studied as its infection of the vaginal tract. However, new study are emerge after the development of molecular biology techniques. The objective of this study is to show the prevalence of HPV in the oral cavity and the oropharynx. An ample bibliographic review was done showing a prevalence of HPV 6, 11 in a normal oral mucous membrane (latent infection). In oral benign lesions associated with HPV, a prevalence of HPV 6 and 11 was observed in squamous cell papilloma (SCP) and condylomas acuminatum, while HPV 2 and 57 were more prevalent in verruca vulgaris lesions. As for focal epithelial hyperplasia (FEH) and oral cancer, especially squamous cell carcinoma (SCC), the prevalence was of HPV 13 and 32, and HPV 16, respectively. The last findings are, nonetheless, controversial. The last findings are, nonetheless, controversial. Showed also discrepancy result the prevalence of human papillomavirus (HPV) in normal oral mucous (latent infection) and in oral cancer, however evidenced confirmatory result in oral benign lesions associated with virus.
人类乳头瘤病毒（HPV）在口腔和口咽中的流行情况尚未像其在阴道感染那样得到充分研究。然而，随着分子生物学技术的发展，新的研究不断涌现。本研究的目的是揭示HPV在口腔和口咽中的流行情况。进行了全面的文献综述，结果显示在正常口腔黏膜中（潜伏感染）HPV 6、11的流行情况。在与HPV相关的口腔良性病变中，鳞状细胞乳头瘤（SCP）和尖锐湿疣中观察到HPV 6和11的流行，而HPV 2和57在寻常疣病变中更为普遍。至于局灶性上皮增生（FEH）和口腔癌，尤其是鳞状细胞癌（SCC），HPV 13和32以及HPV 16的流行情况分别如此。然而，最后的这些发现存在争议。然而，最后的这些发现存在争议。在正常口腔黏膜（潜伏感染）和口腔癌中人类乳头瘤病毒（HPV）的流行情况也显示出差异结果，不过在与病毒相关的口腔良性病变中得到了证实性结果。
