胚胎移植一周后通过三维超声测量子宫内膜厚度和体积以检测妊娠情况。
Endometrial thickness and volume by three-dimensional ultrasound one week after embryo transfer to detect pregnancy.
作者信息
de Paula Martins Wellington, Ferriani Rui Alberto, dos Reis Rosana Maria, Nastri Carolina Oliveira, Filho Francisco Mauad
机构信息
Departamento de Ginecologia e Obstetrícia da Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, São Paulo, Brasil.
出版信息
J Assist Reprod Genet. 2006 Jul-Aug;23(7-8):347-50. doi: 10.1007/s10815-006-9059-8. Epub 2006 Sep 5.
PURPOSE
Determine if the evaluation of endometrium one week after embryo transfer can predict pregnancy.
METHODS
Endometrial volume and thickness were evaluated by three-dimensional ultrasound in 40 patients one week after embryo transfer. These results were compared to serum pregnancy test performed one week later.
RESULTS
Twenty two patients have achieved pregnancy. A significant difference was found for endometrial volume: 6.49+/-1.97 mL vs. 3.40+/-1.11 mL (pregnant vs. not pregnant); and thickness: 11.15+/-2.75 mm vs. 9.77+/-1.85 mm. The ROC curve was used to detect the best cutoff values: endometrial volume of 3.48 mL (sensitivity-100%, specificity-68.2%) and endometrial thickness of 10.3 mm (sensitivity-72.2%, specificity-77.3%). The area under curve was significant higher for endometrial volume (0.909 vs. 0.745, P=0.027). No pregnancy was achieved in women who had an endometrial volume <3.8 mL (15 patients) or thickness < 7.9 mm (3 patients).
CONCLUSIONS
The endometrial volume and thickness were significant higher in pregnant women and this difference was more prominent for endometrial volume.
目的
确定胚胎移植一周后对子宫内膜的评估是否能预测妊娠。
方法
对40例患者在胚胎移植一周后通过三维超声评估子宫内膜体积和厚度。将这些结果与一周后进行的血清妊娠试验结果进行比较。
结果
22例患者成功妊娠。发现子宫内膜体积存在显著差异：6.49±1.97 mL对3.40±1.11 mL（妊娠组对未妊娠组）；以及厚度：11.15±2.75 mm对9.77±1.85 mm。采用ROC曲线检测最佳临界值：子宫内膜体积为3.48 mL（敏感性-100%，特异性-68.2%），子宫内膜厚度为10.3 mm（敏感性-72.2%，特异性-77.3%）。子宫内膜体积的曲线下面积显著更高（0.909对0.745，P = 0.027）。子宫内膜体积<3.8 mL的女性（15例）或厚度<7.9 mm的女性（3例）均未妊娠。
结论
妊娠女性的子宫内膜体积和厚度显著更高，且这种差异在子宫内膜体积方面更为突出。
Zotero 插件