García-Arpa Mónica, Rodríguez-Vázquez María, Sánchez-Caminero Prado, Delgado Margarita, Vera Elena, Romero Guillermo, Cortina Pilar
Servicio de Dermatología, Hospital General de Ciudad Real, España.
Actas Dermosifiliogr. 2006 Jun;97(5):334-6. doi: 10.1016/s0001-7310(06)73413-5.
Cutaneous metastases are infrequent and in some cases represent the first manifestation of an unknown neoplasm. Acrally located metastases are particularly rare, and the prognosis is very poor, with a survival time of only a few months. Although the clinical presentation varies, they are generally confused with an infectious or inflammatory process, which delays diagnosis. When they are located on the fingers, the most frequent cause is lung carcinoma, while those located on the toes are usually due to tumors in the genitourinary tract. The histology of the metastasis is similar to that of the primary tumor, although less differentiated. In most acrometastases, first the bone and then the skin are affected. Treatment is palliative. We present the case of a patient with a metastasis on the big toe as an initial sign of a previously unknown lung tumor.
皮肤转移瘤并不常见，在某些情况下是未知肿瘤的首发表现。肢端转移瘤尤为罕见，预后很差，生存时间仅几个月。尽管临床表现各异，但通常会与感染性或炎症性疾病相混淆，从而延误诊断。当转移瘤位于手指时，最常见的病因是肺癌，而位于脚趾时通常源于泌尿生殖道肿瘤。转移瘤的组织学与原发肿瘤相似，但分化程度较低。在大多数肢端转移瘤中，首先是骨骼然后是皮肤受到影响。治疗是姑息性的。我们报告一例患者，其大脚趾出现转移瘤，是先前未知肺部肿瘤的首发症状。
