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趾部肢端转移作为大细胞肺癌患者转移的初始征象

Toe Acrometastasis as an Initial Sign of Metastasis in a Patient With a Large Cell Lung Carcinoma.

作者信息

Malhame Zakhia Michael, El Rachkidi Rami

机构信息

Department of Orthopaedics and Traumatology, Notre Dame des Secours University Hospital Medical Center, Byblos, LBN.

Department of Orthopaedics and Traumatology, Bhannes Medical Center, Bhannes, LBN.

出版信息

Cureus. 2022 Oct 30;14(10):e30861. doi: 10.7759/cureus.30861. eCollection 2022 Oct.

DOI:10.7759/cureus.30861
PMID:36457597
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9706283/
Abstract

Acrometastases are rare lesions that originate most commonly from the primary lung cancer. They can mislead the diagnosis and the treatment, since they often appear as an osteomyelitis of the affected area. The presence of these metastases is a sign of poor prognosis, with a life expectancy of few months. We report a case of a 78-year-old male with an acrometastasis to the distal phalanx of the right fourth toe. It was the first sign that his previously diagnosed large cell lung carcinoma had reached a metastatic stage. Amputation of the toe was considered in this case where the intense pain of his acrometastasis could not be managed even with strong analgesics.

摘要

肢端转移瘤是一种罕见的病变,最常见于原发性肺癌。它们可能会误导诊断和治疗,因为它们通常表现为受累区域的骨髓炎。这些转移瘤的出现是预后不良的标志,预期寿命只有几个月。我们报告一例78岁男性,其右第四趾远端指骨发生肢端转移瘤。这是他之前诊断的大细胞肺癌已进入转移阶段的首个迹象。在这种情况下,考虑到即使使用强效镇痛药也无法控制其肢端转移瘤的剧痛,遂进行了截趾手术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ffa/9706283/8d0f2eb33d93/cureus-0014-00000030861-i12.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ffa/9706283/0123cd35c79d/cureus-0014-00000030861-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ffa/9706283/95e5fe225a03/cureus-0014-00000030861-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ffa/9706283/6ee510636386/cureus-0014-00000030861-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ffa/9706283/ccf20ac12bc3/cureus-0014-00000030861-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ffa/9706283/e88a8e2ce138/cureus-0014-00000030861-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ffa/9706283/ddd6924cf8b5/cureus-0014-00000030861-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ffa/9706283/b642e2680586/cureus-0014-00000030861-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ffa/9706283/d65e87244505/cureus-0014-00000030861-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ffa/9706283/dcf8fba6203e/cureus-0014-00000030861-i09.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ffa/9706283/7bd5a12d7b03/cureus-0014-00000030861-i10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ffa/9706283/75f2489a7dda/cureus-0014-00000030861-i11.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ffa/9706283/8d0f2eb33d93/cureus-0014-00000030861-i12.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ffa/9706283/0123cd35c79d/cureus-0014-00000030861-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ffa/9706283/95e5fe225a03/cureus-0014-00000030861-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ffa/9706283/6ee510636386/cureus-0014-00000030861-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ffa/9706283/ccf20ac12bc3/cureus-0014-00000030861-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ffa/9706283/e88a8e2ce138/cureus-0014-00000030861-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ffa/9706283/ddd6924cf8b5/cureus-0014-00000030861-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ffa/9706283/b642e2680586/cureus-0014-00000030861-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ffa/9706283/d65e87244505/cureus-0014-00000030861-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ffa/9706283/dcf8fba6203e/cureus-0014-00000030861-i09.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ffa/9706283/7bd5a12d7b03/cureus-0014-00000030861-i10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ffa/9706283/75f2489a7dda/cureus-0014-00000030861-i11.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ffa/9706283/8d0f2eb33d93/cureus-0014-00000030861-i12.jpg

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本文引用的文献

1
Metastatic Lung Cancer to the Distal Finger Presenting as Osteomyelitis.以骨髓炎形式表现的远端手指转移性肺癌
Cureus. 2020 Nov 11;12(11):e11441. doi: 10.7759/cureus.11441.
2
Foot metastasis: Current knowledge.足部转移:当前认知
Orthop Rev (Pavia). 2020 Jun 25;12(Suppl 1):8671. doi: 10.4081/or.2020.8671. eCollection 2020 Jun 29.
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Sclerotic Bone Metastasis in Pulmonary Adenocarcinoma.肺腺癌中的硬化性骨转移
Case Rep Med. 2018 Jun 12;2018:1903757. doi: 10.1155/2018/1903757. eCollection 2018.
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Acrometastasis due to lung adenocarcinoma.肺腺癌所致的肢端转移
Adv Respir Med. 2018;86(2):97-100. doi: 10.5603/ARM.2018.0013.
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Digital Acrometastasis as Initial Presentation in Carcinoma of Lung A Case Report and Review of Literature.以数字性肢端转移为首发表现的肺癌:一例报告并文献复习
J Clin Diagn Res. 2016 Jun;10(6):XD01-XD02. doi: 10.7860/JCDR/2016/16063.7951. Epub 2016 Jun 1.
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Acrometastasis: a literature review.肢端转移:文献综述
Eur Rev Med Pharmacol Sci. 2015 Aug;19(15):2906-15.
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Acrometastases.肢端转移
Eur J Orthop Surg Traumatol. 2014 Apr;24(3):279-83. doi: 10.1007/s00590-013-1311-1. Epub 2013 Sep 8.
8
Two cases of acrometastasis to the hands and review of the literature.手部骨转移 2 例并文献复习
Curr Oncol. 2008 Oct;15(5):51-8. doi: 10.3747/co.v15i5.189.
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Managing acrometastases treatment strategy with a case illustration.通过病例说明来管理肢端转移瘤的治疗策略。
Ann R Coll Surg Engl. 2008 Oct;90(7):W8-11. doi: 10.1308/147870808X303137.
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Palliative surgery of acrometastases from lung cancer: a case report.肺癌肢端转移瘤的姑息性手术:一例报告
Support Care Cancer. 2004 Mar;12(3):202-4. doi: 10.1007/s00520-003-0574-1. Epub 2004 Feb 4.