Kim Sungpyo, Jensen James N, Aga Diana S, Weber A Scott
Department of Civil, Structural, and Environmental Engineering, 212 Ketter Hall, University at Buffalo, The State University of New York, Buffalo, NY 14260, United States.
Chemosphere. 2007 Jan;66(9):1643-51. doi: 10.1016/j.chemosphere.2006.07.066. Epub 2006 Sep 7.
Tetracycline, one of the most widely used antibiotics, is excreted into wastewater after consumption by humans and animals. The focus of this research was to evaluate the fate of tetracycline resistant bacteria in the activated sludge process as a function of tetracycline loading. The studies were conducted with aerobic biological sequencing batch reactors (SBRs). When comparing 250 microgl(-1) tetracycline fed SBRs with parallel SBRs having a background influent wastewater tetracycline concentration of approximately 1 microgl(-1), tetracycline fed reactors were found to have increased concentrations and production rates of tetracycline resistant bacteria, higher net growth rates of resistant bacteria, and higher percentages of tetracycline resistant bacteria, which were amplified by increase in organic loading and growth rates.
四环素是使用最广泛的抗生素之一，人类和动物使用后会排泄到废水中。本研究的重点是评估活性污泥法中四环素抗性细菌的归宿与四环素负荷的关系。研究在好氧生物序批式反应器（SBR）中进行。将投喂250微克/升四环素的SBR与进水四环素背景浓度约为1微克/升的平行SBR进行比较时，发现投喂四环素的反应器中四环素抗性细菌的浓度和产生率增加，抗性细菌的净生长率更高，四环素抗性细菌的百分比更高，这些通过有机负荷和生长率的增加而放大。
