Cano Monica, Bezdudnaya Tatiana, Swadlow Harvey A, Alonso Jose-Manuel
Department of Psychology, University of Connecticut, 406 Babbidge Road, Storrs, Connecticut 06269, USA.
Nat Neurosci. 2006 Oct;9(10):1240-2. doi: 10.1038/nn1760. Epub 2006 Sep 10.
Neuronal responses to visual stimuli depend on both the nature of the stimulus and brain state. Here we examined the contrast sensitivity of visual thalamic neurons as awake rabbits shifted between alert and nonalert states. We found that despite a large increase in response gain with alertness, contrast sensitivity remained nearly constant. This accurate scaling might be achieved through a balanced increase in excitation and inhibition with alertness.
神经元对视觉刺激的反应既取决于刺激的性质，也取决于大脑状态。在这里，我们研究了清醒兔子在警觉和非警觉状态之间转换时，视觉丘脑神经元的对比敏感度。我们发现，尽管随着警觉性的提高反应增益大幅增加，但对比敏感度几乎保持不变。这种精确的缩放可能是通过警觉时兴奋和抑制的平衡增加来实现的。
