Durrant Simon, Feng Jianfeng
Department of Informatics, Sussex University, Brighton, BN1 9QH, UK.
Biol Cybern. 2006 Nov;95(5):431-53. doi: 10.1007/s00422-006-0096-2. Epub 2006 Sep 9.
Lateral inhibition is a well documented aspect of neural architecture in the main sensory systems. Existing accounts of lateral inhibition focus on its role in sharpening distinctions between inputs that are closely related. However, these accounts fail to explain the functional role of inhibition in cortical columns, such as those in V1, where neurons have similar response properties. In this paper, we outline a model of position tracking using cortical columns of integrate-and-fire and Hodgkin-Huxley-type neurons which respond optimally to a particular location, to show that negatively correlated firing patterns arise from lateral inhibition in cortical columns and that this provides a clear benefit for population coding in terms of stability, accuracy, estimation time and neural resources.
侧抑制是主要感觉系统中神经结构的一个有充分记录的方面。现有的关于侧抑制的描述主要集中在其在锐化密切相关输入之间差异方面的作用。然而，这些描述未能解释抑制在皮质柱（如初级视皮层V1区的皮质柱）中的功能作用，在这些皮质柱中神经元具有相似的反应特性。在本文中，我们概述了一个使用积分发放和霍奇金-赫胥黎型神经元的皮质柱进行位置跟踪的模型，这些神经元对特定位置具有最佳反应，以表明负相关的发放模式源于皮质柱中的侧抑制，并且这在稳定性、准确性、估计时间和神经资源方面为群体编码提供了明显的优势。
