Stava Charles J, Lopez Adriana, Vassilopoulou-Sellin Rena
Department of Endocrine Neoplasia and Hormonal Disorders, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.
Cancer. 2006 Oct 15;107(8):1752-9. doi: 10.1002/cncr.22200.
Over the past several decades, the incidence of prolonged survival after a diagnosis of cancer has increased; however, little is known regarding the long-term health profiles of cancer survivors in general and of breast cancer survivors in particular. To obtain more information concerning the consequences of surviving breast cancer, the authors conducted a large-scale health survey of patients who had been treated for the disease at their institution.
A descriptive analysis of information was provided by cancer survivors. Of the breast cancer survivors who were studied, 695 women were age < 45 years, 580 women were between ages 46 years and 54 years, and 655 women were age > 55 years at the time of diagnosis. Their medical and psychosocial responses were analyzed and compared with those of age-matched responders in a national survey.
Younger breast cancer survivors received chemotherapy more often than older survivors and were more likely to report memory loss and that cancer had affected their overall health adversely. Several other differences in physiologic and psychosocial characteristics, such as interpersonal relationships, also emerged.
Physiologic and psychosocial differences distinguished younger breast cancer survivors from older breast cancer survivors. The findings of this study suggested that a systematic analysis of cancer survivors is needed to understand their unique health profiles and needs.
在过去几十年中，癌症诊断后长期存活的发生率有所增加；然而，对于癌症幸存者总体，尤其是乳腺癌幸存者的长期健康状况知之甚少。为了获取更多关于乳腺癌存活后果的信息，作者对在其机构接受过该疾病治疗的患者进行了一项大规模健康调查。
癌症幸存者提供了信息的描述性分析。在接受研究的乳腺癌幸存者中，695名女性在诊断时年龄小于45岁，580名女性年龄在46岁至54岁之间，655名女性年龄大于55岁。分析了她们的医疗和心理社会反应，并与全国调查中年龄匹配的应答者的反应进行了比较。
较年轻的乳腺癌幸存者比年长的幸存者更常接受化疗，并且更有可能报告记忆力减退以及癌症对其整体健康产生了不利影响。在生理和心理社会特征方面还出现了其他一些差异，例如人际关系。
生理和心理社会差异区分了年轻乳腺癌幸存者和年长乳腺癌幸存者。这项研究的结果表明，需要对癌症幸存者进行系统分析，以了解他们独特的健康状况和需求。
