May Andrea, Nachbar Lars, Schneider Marion, Ell Christian
Department of Internal Medicine II, HSK Wiesbaden, Teaching Hospital of the University of Mainz, Wiesbaden, Germany.
Am J Gastroenterol. 2006 Sep;101(9):2016-24. doi: 10.1111/j.1572-0241.2006.00745.x.
The management of patients with suspected mid-gastrointestinal bleeding has in the past been difficult, as push enteroscopy (PE) only allows limited endoscopic access for diagnosis and treatment. Recently published uncontrolled data on push-and-pull enteroscopy (PPE) using the double-balloon technique suggest that this new method has a high diagnostic yield and therapeutic efficacy. A prospective controlled study was therefore carried out to compare PPE with PE as the common nonsurgical gold standard method.
The diagnostic yield, complications, and various examination parameters were compared in 52 consecutive patients with suspected mid-gastrointestinal bleeding who were evaluated with both enteroscopy methods.
No relevant complications were observed with either method. Sedoanalgesia, examination times, and X-ray exposure were lower with PE. The insertion depth was significantly greater with PPE than with PE (230 cm vs 80 cm, p < 0.0001). The overall diagnostic yield with PPE (38 of 52 patients, 73%) and the results of oral PPE only (33 of 52 patients, 63%) were superior to those with PE (23 of 52 patients, 44%; p < 0.0001). PPE identified additional lesions in deeper parts of the small bowel in PE-positive patients in 78% of cases (18 of 23 patients).
For endoscopic examination of the small bowel in patients with suspected mid-gastrointestinal bleeding, PPE is superior to PE with regard to the length of small bowel visualized, as well as the diagnostic yield. As the method also allows endoscopic treatment to be carried out, PPE should always be considered before open surgery and intraoperative endoscopy in patients with mid-gastrointestinal bleeding.
过去,疑似中消化道出血患者的管理颇具难度,因为推进式小肠镜检查(PE)仅能提供有限的内镜检查途径用于诊断和治疗。最近发表的关于使用双气囊技术的推拉式小肠镜检查(PPE)的非对照数据表明,这种新方法具有较高的诊断率和治疗效果。因此,开展了一项前瞻性对照研究,以比较PPE与作为常用非手术金标准方法的PE。
对52例连续的疑似中消化道出血患者采用两种小肠镜检查方法进行评估,比较其诊断率、并发症及各项检查参数。
两种方法均未观察到相关并发症。PE的镇静镇痛效果、检查时间及X线暴露量较低。PPE的插入深度显著大于PE(230 cm对80 cm,p < 0.0001)。PPE的总体诊断率(52例患者中的38例,73%)及仅口服PPE的结果(52例患者中的33例,63%)优于PE(52例患者中的23例,44%;p < 0.0001)。在PE检查阳性的患者中,PPE在78%的病例(23例患者中的18例)中发现了小肠深部的额外病变。
对于疑似中消化道出血患者的小肠内镜检查,在可视小肠长度及诊断率方面,PPE优于PE。由于该方法还允许进行内镜治疗,对于中消化道出血患者,在进行开放手术和术中内镜检查之前,应始终考虑PPE。