Vos Gijs, Engel Monique, Ramsay Graham, van Waardenburg Dick
Department of Pediatrics, Division of Pediatric Intensive Care, University Hospital Maastricht, Maastricht, The Netherlands.
Eur J Emerg Med. 2006 Oct;13(5):304-7. doi: 10.1097/00063110-200610000-00013.
To investigate the influence of point-of-care laboratory results (arterial blood gases, ionized calcium, potassium, sodium, glucose, hematocrit and hemoglobin) on therapeutic interventions during interhospital pediatric intensive care transport.
Prospective observational study.
Specialist pediatric intensive care retrieval team of a university hospital.
Critically ill pediatric patients who were referred from a community hospital to a pediatric intensive care of a tertiary center. The retrieval team sampled arterial blood during the time of stabilization in the referring hospital and during transport. All results were recorded and for each result the physician of the specialist retrieval team wrote down the influence on the treatment (none, partly, only). The physician specified the kind of intervention.
Point-of-care blood analyses influenced the therapeutic management in 76.5% of all blood samples and in 86.2% of the referred patients. Of all interventions, 42.9% were based only on the laboratory results. The majority of interventions were adjustments of the mechanical ventilation. Point-of-care blood analyses reduced the delay in treatment of potentially life-threatening abnormalities of laboratory results (severe hypokalemia and low hematocrit).
During interhospital pediatric intensive care transport, point-of-care blood analyses frequently led to therapeutic interventions. Some abnormal blood results were potentially life threatening and could not have been discovered without point-of-care measurement. We therefore recommend the use of a point-of-care blood analyzer during interhospital intensive care transports, not only for blood gases but also for electrolytes, glucose and hematocrit.
探讨床旁实验室检查结果(动脉血气、离子钙、钾、钠、葡萄糖、血细胞比容和血红蛋白)对院际小儿重症监护转运期间治疗干预措施的影响。
前瞻性观察性研究。
某大学医院的专科小儿重症监护转运团队。
从社区医院转诊至三级中心小儿重症监护病房的危重症患儿。转运团队在转诊医院稳定患儿病情期间及转运过程中采集动脉血样。记录所有结果,对于每项结果,专科转运团队的医生记录其对治疗的影响(无影响、部分影响、仅影响)。医生明确干预措施的类型。
床旁血液分析对所有血样中76.5%以及转诊患儿中86.2%的治疗管理产生影响。在所有干预措施中,42.9%仅基于实验室检查结果。大多数干预措施是对机械通气的调整。床旁血液分析减少了对实验室检查结果中潜在危及生命异常情况(严重低钾血症和低血细胞比容)治疗的延迟。
在院际小儿重症监护转运期间,床旁血液分析经常导致治疗干预。一些异常血液结果可能危及生命,若没有床旁检测则无法发现。因此,我们建议在院际重症监护转运期间使用床旁血液分析仪,不仅用于血气分析,还用于电解质、葡萄糖和血细胞比容检测。