Jain Anunaya, Subhan Imron, Joshi Mahesh
College of Medicine, Mayo Clinic, Rochester, MN, USA.
Int J Emerg Med. 2009 Feb 24;2(2):117-20. doi: 10.1007/s12245-009-0091-1.
Electrolyte values are measured both by arterial blood gas (ABG) analyzers and central laboratory auto-analyzers (AA), but a significant time gap exists between the availability of both these results, with the ABG giving faster results than the AA. The authors hypothesized that there is no difference between the results obtained after measurement of electrolytes by the blood gas and auto-analyzers.
After approval by the ethics committee, an observational cohort study was conducted in which 200 paired venous and arterial samples from patients admitted to the Medical Intensive Care Unit (ICU) of Apollo Hospital, Hyderabad, India, were analyzed for electrolytes on the ABG machine and the AA. Analyses were done on the ABL555 blood gas analyzer and the Dade Dimension RxL Max, both located in the central laboratory. Statistical analyses were performed using paired Student's t test.
A total of 200 paired samples were analyzed. The mean ABG sodium value was 131.28 (SD 7.33), and the mean AA sodium value was 136.45 (SD 6.50) (p < 0.001). The mean ABG potassium value was 3.74 (SD 1.92), and the mean AA potassium value was 3.896 (SD 1.848) (p = 0.2679).
Based on the above analysis, the authors found no significant difference between the potassium values measured by the blood gas machine and the auto-analyzer. However, the difference between the measured sodium was found to be significant. We therefore conclude that critical decisions can be made by trusting the potassium values obtained from the arterial blood gas analysis.
电解质值可通过动脉血气（ABG）分析仪和中心实验室自动分析仪（AA）进行测量，但这两种结果的可得时间存在显著差距，ABG得出结果的速度比AA快。作者推测，通过血气分析仪和自动分析仪测量电解质后获得的结果之间没有差异。
经伦理委员会批准后，开展了一项观察性队列研究，对印度海得拉巴阿波罗医院医学重症监护病房（ICU）收治患者的200对静脉和动脉样本在ABG机器和AA上进行电解质分析。分析在均位于中心实验室的ABL555血气分析仪和Dade Dimension RxL Max上进行。使用配对学生t检验进行统计分析。
共分析了200对样本。ABG测得的钠平均值为131.28（标准差7.33），AA测得的钠平均值为136.45（标准差6.50）（p<0.001）。ABG测得的钾平均值为3.74（标准差1.92），AA测得的钾平均值为3.896（标准差1.848）（p=0.2679）。
基于上述分析，作者发现血气分析仪和自动分析仪测得的钾值之间无显著差异。然而，测得的钠值之间的差异是显著的。因此，我们得出结论，可信赖从动脉血气分析获得的钾值来做出关键决策。
