Remy André-Jean
Unité de Consultations et de Soins Ambulatoires (UCSA), Service d'Hépato-Gastroentérologie et de Cancérologie Digestive, Réseau Hépatite C de Catalogne et du Pays d'Oc, Centre Hospitalier Saint-Jean Roussillon, Perpignan.
Presse Med. 2006 Sep;35(9 Pt 1):1249-54. doi: 10.1016/s0755-4982(06)74797-2.
To determine the real frequency of hepatitis C (HCV) in French prisons.
To evaluate the changes in HCV screening and therapeutic practices in prisons between 2000 and 2003 by comparing results of mail surveys of prison medical units both years (* if p<0.01).
88 units (51%) responded to both surveys. In 2003, HCV serologic screening was routinely performed in 28% (36%* in 2000) of prisons and routinely offered in 66% (35%). Mean HCV prevalence was 6.9% in 2003 and 6.7% in 2003. There were 534 liver biopsies in 2003 and 545 in 2003, that is, an average of 6 biopsies per unit per year both years. Treatment was provided to 297 patients in 2003 and 164 in 2000, but 29% of prisons offered no treatment in 2003, and 44% () in 2000. Overall 14% of HCV-infected prisoners received therapy.
The prisons participating in this study and the inmates they include were representative of the French prison population. HCV prevalence in French prisons appears stable. Routinely suggested or conducted screening is widespread. The number of liver biopsies is stable but low, and the number of patients receiving treatment has increased significantly.
确定法国监狱中丙型肝炎(HCV)的实际感染率。
通过比较2000年和2003年监狱医疗单位邮件调查结果,评估这两年间监狱中HCV筛查和治疗实践的变化(*若p<0.01)。
88个单位(51%)回复了两次调查。2003年,28%(2000年为36%)的监狱常规进行HCV血清学筛查,66%(2000年为35%)的监狱常规提供筛查。2003年HCV平均感染率为6.9%,2000年为6.7%。2003年有534例肝脏活检,2000年有545例,即这两年每个单位每年平均有6例活检。2003年有297名患者接受治疗,2000年有164名,但2003年29%的监狱不提供治疗,2000年为44%(*)。总体而言,14%的HCV感染囚犯接受了治疗。
参与本研究的监狱及其所关押的囚犯代表了法国监狱人口。法国监狱中HCV感染率似乎稳定。常规建议或进行的筛查很普遍。肝脏活检数量稳定但较低,接受治疗的患者数量显著增加。