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患有血液系统疾病的感染牛白血病病毒(BLV)的绵羊的B细胞表达CD5 T细胞标志物。

B cells from bovine leukemia virus- (BLV) infected sheep with hematological disorders express the CD5 T cell marker.

作者信息

Letesson J J, Mager A, Mammerickx M, Burny A, Depelchin A

机构信息

Microbiology and Immunology Unit, Universite Notre Dame de la Paix Namur, Belgium.

出版信息

Leukemia. 1990 May;4(5):377-9.

PMID:1697010
Abstract

Though peripheral blood B cells from healthy sheep were known to be devoid of the CD5 T cell marker, it appears from our study that most B cells from bovine leukemia virus- (BLV) infected sheep with hematological disorders express both the CD5 marker and surface IgM. The possible meaning of this T cell marker expression on B cells from BLV-infected sheep is briefly discussed.

摘要

虽然已知健康绵羊的外周血B细胞缺乏CD5 T细胞标志物,但从我们的研究来看,大多数患有血液系统疾病的感染牛白血病病毒(BLV)的绵羊的B细胞同时表达CD5标志物和表面IgM。本文简要讨论了BLV感染绵羊的B细胞上这种T细胞标志物表达的可能意义。

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