Teng C L, Nik-Sherina Hanafi, Ng C J, Chia Y C, Atiya Abdul Sallam
Department of Family Medicine, International Medical University, Seremban, Malaysia.
J Paediatr Child Health. 2006 Oct;42(10):612-7. doi: 10.1111/j.1440-1754.2006.00937.x.
Fever in children, a mostly benign and self-limiting illness, is often viewed with consternation by the care givers. It results in early consultation and excessive use of antipyretics and antibiotics. In this study, we document the prescribing practice of doctors from three primary care settings in Malaysia and identify the predictors of antibiotic prescription.
Interview of care givers bringing febrile children (age </= 12 years) to three primary care settings: public primary care clinics, private general practice clinics and a university-based primary care clinic.
Data from 649 children were analysed. Mean age of children 4.1 years and 55% were boys. One-third of the children had prior consultation for the same episode of fever. About 80% of the febrile children were diagnosed to have upper respiratory tract infection, viral fever and gastroenteritis. Overall antibiotic prescribing rate was 36.6% (public primary care clinic 26.8%, private general practice clinic 70.0% and university-based primary care clinic 32.2%). Independent predictors of antibiotic prescription were: clinic setting, longer duration of fever (>7 days), higher temperature (>38 degrees C) and the diagnosis of upper respiratory tract infections. After controlling for demographic and clinical factors, antibiotic prescription in private general practice clinic was seven times higher than public primary care clinic (odds ratio 7.1, 95% confidence interval 4.0-12.7), and 1.6 times higher than university-based primary care clinic (odds ratio 1.6, 95% confidence interval 1.0-2.5).
Differences in the patients' demographic and clinical characteristics could not adequately explain the high antibiotic prescribing rate in private general practice clinics. This inappropriately high antibiotic prescribing for febrile children in private general practice clinics is a suitable target for future intervention.
儿童发热大多是良性自限性疾病,但看护者往往对此感到恐慌。这导致过早就诊以及退烧药和抗生素的过度使用。在本研究中,我们记录了马来西亚三个基层医疗场所医生的处方行为,并确定抗生素处方的预测因素。
对带发热儿童(年龄≤12岁)前往三个基层医疗场所的看护者进行访谈,这三个场所分别是公立基层医疗诊所、私立全科诊所和大学附属基层医疗诊所。
分析了649名儿童的数据。儿童平均年龄为4.1岁,55%为男孩。三分之一的儿童因同一发热事件曾就诊。约80%的发热儿童被诊断为上呼吸道感染、病毒性发热和肠胃炎。总体抗生素处方率为36.6%(公立基层医疗诊所为26.8%,私立全科诊所为70.0%,大学附属基层医疗诊所为32.2%)。抗生素处方的独立预测因素为:诊所类型、发热持续时间较长(>7天)、体温较高(>38摄氏度)以及上呼吸道感染的诊断。在控制了人口统计学和临床因素后,私立全科诊所的抗生素处方率比公立基层医疗诊所高7倍(比值比7.1,95%置信区间4.0 - 12.7),比大学附属基层医疗诊所高1.6倍(比值比1.6,95%置信区间1.0 - 2.5)。
患者的人口统计学和临床特征差异不足以解释私立全科诊所抗生素高处方率的现象。私立全科诊所对发热儿童不恰当的高抗生素处方率是未来干预的合适目标。