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Raised plasma N-terminal pro-B-type natriuretic peptide concentrations predict mortality and cardiac disease in end-stage renal disease.血浆N末端B型利钠肽原浓度升高可预测终末期肾病患者的死亡率和心脏疾病。
Heart. 2006 Oct;92(10):1518-9. doi: 10.1136/hrt.2005.082313.
2
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The relationship between N-terminal pro-brain natriuretic peptide and risk for hospitalization and mortality is curvilinear in patients with chronic heart failure.在慢性心力衰竭患者中，N 末端前脑钠肽与住院风险和死亡率之间的关系呈曲线相关。
Am Heart J. 2007 Jul;154(1):123-9. doi: 10.1016/j.ahj.2007.04.002.
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Comparison of the prognostic usefulness of N-terminal pro-brain natriuretic Peptide in patients with heart failure with versus without chronic kidney disease.N末端脑钠肽前体在合并与未合并慢性肾脏病的心力衰竭患者中预后价值的比较
Am J Cardiol. 2008 Aug 15;102(4):469-74. doi: 10.1016/j.amjcard.2008.03.082. Epub 2008 May 24.
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Comparison of midregional pro-atrial natriuretic peptide with N-terminal pro-B-type natriuretic peptide in predicting survival in patients with chronic heart failure.比较中段心房利钠肽原与N末端B型利钠肽原在预测慢性心力衰竭患者生存率中的作用
J Am Coll Cardiol. 2007 Nov 13;50(20):1973-80. doi: 10.1016/j.jacc.2007.08.012. Epub 2007 Oct 29.
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Early and sustained effects of cardiac resynchronization therapy on N-terminal pro-B-type natriuretic peptide in patients with moderate to severe heart failure and cardiac dyssynchrony.心脏再同步治疗对中重度心力衰竭和心脏不同步患者N末端B型利钠肽前体的早期及持续影响
Eur Heart J. 2007 Jul;28(13):1592-7. doi: 10.1093/eurheartj/ehl505. Epub 2007 Feb 13.
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N-terminal pro-brain natriuretic peptide: an independent risk predictor of cardiovascular congestion, mortality, and adverse cardiovascular outcomes in chronic peritoneal dialysis patients.N 端前脑钠肽：慢性腹膜透析患者心血管充血、死亡率及不良心血管结局的独立风险预测因子。
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Diagnostic value of N-terminal pro-B-type natriuretic peptide (NT-proBNP) for left ventricular dysfunction in patients with chronic kidney disease stage 5 on haemodialysis.N末端B型利钠肽原（NT-proBNP）对慢性肾脏病5期血液透析患者左心室功能障碍的诊断价值
Nephrol Dial Transplant. 2008 Apr;23(4):1370-7. doi: 10.1093/ndt/gfm700. Epub 2007 Dec 18.
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Diagnostic potential of serum biomarkers for left ventricular abnormalities in chronic peritoneal dialysis patients.慢性腹膜透析患者血清生物标志物对左心室异常的诊断潜力
Nephrol Dial Transplant. 2009 Jun;24(6):1962-9. doi: 10.1093/ndt/gfp067. Epub 2009 Feb 23.
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Pro-B-type natriuretic peptide levels in acute decompensated heart failure.急性失代偿性心力衰竭患者的前B型利钠肽水平
J Am Coll Cardiol. 2008 May 13;51(19):1874-82. doi: 10.1016/j.jacc.2007.12.051.

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The Impact of Volume Removal by Hemodialysis on Elevated NT-proBNP Levels in Patients With Hypervolemia.血液透析清除容量对高血容量患者升高的NT-proBNP水平的影响
Cureus. 2025 Jun 8;17(6):e85554. doi: 10.7759/cureus.85554. eCollection 2025 Jun.
2
Do Natriuretic Peptide Measurements Provide Insights into Management of End-Stage Renal Disease Patients Undergoing Dialysis?利钠肽测量能否为透析终末期肾病患者的管理提供新视角？
Curr Heart Fail Rep. 2020 Dec;17(6):449-456. doi: 10.1007/s11897-020-00488-6. Epub 2020 Sep 17.
3
Prognostic utility of NT-proBNP greater than 70,000 pg/mL in patients with end stage renal disease.NT-proBNP大于70,000 pg/mL在终末期肾病患者中的预后效用。
J Geriatr Cardiol. 2018 Jul;15(7):476-478. doi: 10.11909/j.issn.1671-5411.2018.07.002.
4
Inverse relationship of bone mineral density and serum level of N-terminal pro-B-type natriuretic peptide in peritoneal dialysis patients.腹膜透析患者骨矿物质密度与血清N末端B型利钠肽原水平的负相关关系。
Tzu Chi Med J. 2016 Apr-Jun;28(2):68-72. doi: 10.1016/j.tcmj.2016.03.003. Epub 2016 May 28.
5
B-type natriuretic peptide and prognosis of end-stage renal disease: a meta-analysis.B 型利钠肽与终末期肾病预后：荟萃分析。
PLoS One. 2013 Nov 13;8(11):e79302. doi: 10.1371/journal.pone.0079302. eCollection 2013.
6
Association between N-terminal pro-brain natriuretic peptide and acute ischemic stroke in patients on chronic hemodialysis.慢性血液透析患者 N 端脑利钠肽前体与急性缺血性卒中的关系。
Int Urol Nephrol. 2010 Jun;42(2):537-43. doi: 10.1007/s11255-009-9689-8. Epub 2009 Dec 29.

本文引用的文献

1
Dobutamine stress echocardiography and cardiac troponin T for the detection of significant coronary artery disease and predicting outcome in renal transplant candidates.多巴酚丁胺负荷超声心动图及心肌肌钙蛋白T用于检测肾移植候选者的严重冠状动脉疾病及预测预后
Eur J Echocardiogr. 2005 Oct;6(5):327-35. doi: 10.1016/j.euje.2005.04.011.
2
N-terminal pro-B-type natriuretic peptide for predicting coronary disease and left ventricular hypertrophy in asymptomatic CKD not requiring dialysis.N末端前B型利钠肽用于预测无需透析的无症状慢性肾脏病患者的冠心病和左心室肥厚。
Am J Kidney Dis. 2005 Jul;46(1):35-44. doi: 10.1053/j.ajkd.2005.04.007.
3
The N-terminal Pro-BNP investigation of dyspnea in the emergency department (PRIDE) study.急诊科N端前脑钠肽对呼吸困难的研究（PRIDE研究）
Am J Cardiol. 2005 Apr 15;95(8):948-54. doi: 10.1016/j.amjcard.2004.12.032.
4
Multi-biomarker risk stratification of N-terminal pro-B-type natriuretic peptide, high-sensitivity C-reactive protein, and cardiac troponin T and I in end-stage renal disease for all-cause death.N末端B型利钠肽原、高敏C反应蛋白以及心肌肌钙蛋白T和I对终末期肾病全因死亡的多生物标志物风险分层
Clin Chem. 2004 Dec;50(12):2279-85. doi: 10.1373/clinchem.2004.035741. Epub 2004 Sep 13.
5
Reference ranges for natriuretic peptides for diagnostic use are dependent on age, gender and heart rate.用于诊断的利钠肽参考范围取决于年龄、性别和心率。
Eur J Heart Fail. 2003 Oct;5(5):599-606. doi: 10.1016/s1388-9842(03)00108-9.

Raised plasma N-terminal pro-B-type natriuretic peptide concentrations predict mortality and cardiac disease in end-stage renal disease.

作者信息

Sharma R, Gaze D C, Pellerin D, Mehta R L, Gregson H, Streather C P, Collinson P O, Brecker S J D

出版信息

Heart. 2006 Oct;92(10):1518-9. doi: 10.1136/hrt.2005.082313.

DOI:10.1136/hrt.2005.082313
PMID:16973808
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1861028/
Abstract
摘要