King C C
Department of Mathematics and Statistics, University of Auckland.
Orig Life Evol Biosph. 1990;20(1):15-25. doi: 10.1007/BF01808056.
The discovery of RNA-based enzymes, such as ribonuclease-P, has stimulated new interest in the idea that catalytic functions of RNA preceded the use of coded enzymes during an era loosely termed 'the RNA world'. This paper examines various lines of evidence which support the idea that electrochemical processes associated with the membrane may have preceded the development of coded protein enzymes and may have provided a basis for the phosphorylation energy of the RNA world.
诸如核糖核酸酶P等基于RNA的酶的发现,激发了人们对以下观点的新兴趣:在一个大致称为“RNA世界”的时代,RNA的催化功能先于编码酶的使用。本文研究了各种证据,这些证据支持以下观点:与膜相关的电化学过程可能先于编码蛋白酶的发展,并且可能为RNA世界的磷酸化能量提供了基础。