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[子宫颈癌患者的抗体]

[Antibodies in patients with cervicouterine carcinoma].

作者信息

Gomez-Estrada H, Huerta-Sanchez R, Hernandez-Sanchez R, Garza-Eufrasio O, Venustiano-Carranza J, Miranda-Acevedo C, Terrazas-Flores J A, Fernandez-Quintero P

出版信息

Arch Invest Med (Mex). 1975;6(1):13-22.

PMID:169759
Abstract

Cervical smears and serum samples were obtained from 28 ABO compatible patients with carcinoma of the cervix (CaCx) in O to IV clinical stages. Serum IgG antibodies against autologous CaCx cells were detected by immunofluorescence reactions in 24/24 patients with carcinoma of the cervix in I to IV clinical stages. These antibodies also reacted against alogeneic CaCx cells 53/54. Negative reactions were obtained n 4/4 cases of carcinoma of the cervix in stage O, and in control group, 10 normal persons and in 33 neoplastic sera from patients with other malignancies. Hence, detection of serum antibodies against CaCx cells could be an additional tool for CaCx detection.

摘要

从28例临床分期为0至IV期的ABO血型相容的宫颈癌(CaCx)患者中获取宫颈涂片和血清样本。通过免疫荧光反应在24/24例临床分期为I至IV期的宫颈癌患者中检测到针对自体CaCx细胞的血清IgG抗体。这些抗体也与53/54的异基因CaCx细胞发生反应。在0期宫颈癌的4/4例病例、对照组的10名正常人和33例其他恶性肿瘤患者的肿瘤血清中均获得阴性反应。因此,检测针对CaCx细胞的血清抗体可能是CaCx检测的一种辅助手段。

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