van den Ende Esther D, Allema Jan-Hein, Hazebroek Frans W J, Breslau Paul J
Department of Surgery, Haga Hospital, Red Cross Hospital/Juliana Children's Hospital, Sportlaan 600, The Hague, The Netherlands.
Eur J Pediatr. 2007 Jun;166(6):553-7. doi: 10.1007/s00431-006-0277-y. Epub 2006 Sep 15.
In order to document the incidence of perioperative complications in patients with infantile hypertrophic pyloric stenosis, a descriptive cohort study was performed in two teaching hospitals in the Netherlands. One hospital specialized in pediatric surgery and the other was a general surgery teaching hospital. All consecutive infants who underwent pyloromyotomy for the diagnosis hypertrophic pyloric stenosis in both hospitals between 1998 and 2002 were included. The children were diagnosed and treated according to a standard protocol. From all charts, complications durante- and post-operationem were recorded. A total of 256 pyloromyotomies were performed. Registered perioperative complications were duodenal mucosal perforation (n=6; 2%). Perioperatively unrecognized duodenal mucosal perforation occurred four times (1%). One re-operation was performed for an incomplete pyloromyotomy (0.3%). Persistent vomiting after the operation occurred in 18 children (7%). A large majority of postoperative complications were wound infections (n=16; 6%), 12 after right upper quadrant incision and 4 after umbilical incision; most of them were treated with antibiotics and/or incision for drainage of an abscess. An incisional hernia occurred four times. Prolonged vomiting was the only postoperative complication that differed significantly between the two teaching hospitals. The overall percentages of complications were equal to complication rates in literature, and since there were no extensive differences in major complications between the two teaching hospitals in this study, we can conclude that pyloromyotomy can be performed safely in specialized centers and in general centers provided with a multidisciplinary team.
为记录婴儿肥厚性幽门狭窄患者围手术期并发症的发生率,在荷兰的两家教学医院开展了一项描述性队列研究。一家医院专门从事小儿外科,另一家是普通外科教学医院。纳入了1998年至2002年间在这两家医院因诊断为肥厚性幽门狭窄而接受幽门肌切开术的所有连续婴儿。这些儿童按照标准方案进行诊断和治疗。从所有病历中记录术中及术后并发症。共进行了256例幽门肌切开术。记录的围手术期并发症有十二指肠黏膜穿孔(n = 6;2%)。围手术期未识别的十二指肠黏膜穿孔发生了4次(1%)。因幽门肌切开术不完全进行了1次再次手术(0.3%)。术后持续呕吐发生在18名儿童中(7%)。术后并发症大多数是伤口感染(n = 16;6%),右上腹切口后12例,脐部切口后4例;大多数用抗生素和/或切开引流脓肿治疗。切口疝发生了4次。持续呕吐是两家教学医院之间唯一有显著差异的术后并发症。并发症的总体百分比与文献中的并发症发生率相当,并且由于本研究中两家教学医院在主要并发症方面没有广泛差异,我们可以得出结论,在配备多学科团队的专科中心和普通中心都可以安全地进行幽门肌切开术。