Devys J-M, Schauvliège F, Taylor G, Plaud B
Department of Anesthesiology and Intensive Care, Adolphe de Rothschild Fondation, Paris cedex, France.
Paediatr Anaesth. 2004 Aug;14(8):676-80. doi: 10.1111/j.1460-9592.2004.01288.x.
Tracheal mucosal damage related to tracheal intubation has been widely described in pediatric and adult patients. High volume-low pressure cuffs (HVLPC) are being advertised as safe to avoid this particularly unpleasant complication. Compliances of these supposed pediatric and adult HVLPC are not mentioned by manufacturers and still remain unknown.
The compliance of HVLPC was measured in vitro and defined as the straight portion of the pressure-volume curve. Cuff pressure was measured after incremental 0.1 ml filling volumes of air for sizes 3.0-8.0 of internal diameter of Rüsch and Mallinckrodt tracheal tubes. Compliances were assessed in air and in a rigid tube. The filling volume to achieve a 25-mmHg intracuff pressure was also measured.
In air, each 0.1 ml step almost linearly increased cuff pressure by 1 mmHg (size 8.0) to 9 mmHg (size 3). In air, the volume needed to maintain a cuff pressure < 25 mmHg was small for sizes 3-5.5 (0.35-2 ml). The 25 mmHg inflated cuff volume and compliance were decreased within a rigid tube, especially for adult sizes. In a rigid tube simulating a trachea, the compliances of almost every Rüsch tracheal tube were statistically higher than those of the Mallinckrodt.
We conclude that the tested tracheal tube cuffs have low compliance and cannot be defined as high volume-low pressure.
气管插管相关的气管黏膜损伤在儿科和成年患者中已有广泛报道。大容量低压袖带(HVLPC)被宣传为可安全避免这一特别令人不适的并发症。然而,这些所谓的儿科和成人HVLPC的顺应性,制造商并未提及,目前仍不清楚。
在体外测量HVLPC的顺应性,并将其定义为压力-容积曲线的直线部分。对于内径为3.0 - 8.0的Rüsch和Mallinckrodt气管导管,每次以0.1 ml的增量向气囊内充气后测量气囊压力。在空气中和刚性管中评估顺应性。还测量了达到25 mmHg气囊内压力所需的充气量。
在空气中,每增加0.1 ml,气囊压力几乎呈线性增加,从8.0号导管的1 mmHg到3号导管的9 mmHg。在空气中,对于3 - 5.5号导管,维持气囊压力< 25 mmHg所需的气量较小(0.35 - 2 ml)。在刚性管中,25 mmHg充气时的气囊容积和顺应性降低,尤其是成人尺寸的导管。在模拟气管的刚性管中,几乎每个Rüsch气管导管的顺应性在统计学上都高于Mallinckrodt导管。
我们得出结论,所测试的气管导管气囊顺应性低,不能定义为大容量低压。