Paterson Andrew H, Chapman Brad A, Kissinger Jessica C, Bowers John E, Feltus Frank A, Estill James C
Plant Genome Mapping Laboratory and Department of Genetics, University of Georgia, Athens, GA 30602, USA.
Trends Genet. 2006 Nov;22(11):597-602. doi: 10.1016/j.tig.2006.09.003. Epub 2006 Sep 18.
Genome duplication is potentially a good source of new genes, but such genes take time to evolve. We have found a group of "duplication-resistant" genes, which have undergone convergent restoration to singleton status following several independent genome duplications. Restoration of duplication-resistant genes to singleton status could be important to long-term survival of a polyploid lineage. Angiosperms show more frequent polyploidization and a higher degree of duplicate gene preservation than other paleopolyploids, making them well-suited to further study of duplication-resistant genes.
基因组复制可能是新基因的一个良好来源，但这类基因需要时间来进化。我们发现了一组“抗复制”基因，它们在经历了几次独立的基因组复制后，已趋同恢复为单拷贝状态。抗复制基因恢复为单拷贝状态可能对多倍体系的长期生存很重要。被子植物比其他古多倍体表现出更频繁的多倍体化和更高程度的重复基因保留，这使得它们非常适合进一步研究抗复制基因。
