Yamamoto S, Senzaki A, Yamagiwa K, Tanaka T, Oda T
Department of Urology, Kinan General Hospital.
Hinyokika Kiyo. 1990 May;36(5):617-22.
We report a case of carcinoma of the prostate in a 30-year-old man. Serum acid phosphatase was normal. A transrectal biopsy of the prostate demonstrated an undifferentiated carcinoma. Total prostatocystectomy was performed and subsequent pathologic report stated that the mass was an undifferentiated carcinoma of the prostate gland. Metastases to the intrapelvic lymph node were present. Although immunohistochemical prostatic acid phosphatase (PAP) activity was not demonstrated, prostatic specific antigen (PSA) staining revealed a positive reaction within the tumor cells, confirming prostatic carcinoma. The patient's course has been uneventful without any recurrence by the intermittent adjuvant chemotherapy 8 months postoperatively. Review of the literature in Japan disclosed 16 cases (including our case) of carcinoma of the prostate in patients under 40 years of age.
我们报告一例30岁男性前列腺癌病例。血清酸性磷酸酶正常。经直肠前列腺活检显示为未分化癌。行全前列腺膀胱切除术,随后的病理报告表明肿块是前列腺未分化癌。存在盆腔内淋巴结转移。虽然未显示免疫组化前列腺酸性磷酸酶(PAP)活性,但前列腺特异性抗原(PSA)染色显示肿瘤细胞内有阳性反应,证实为前列腺癌。术后8个月通过间歇性辅助化疗,患者病情平稳,无任何复发。对日本文献的回顾发现40岁以下患者中有16例(包括我们的病例)前列腺癌。