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前列腺癌:多年轻算太年轻?

Prostate Cancer: How Young is too Young?

作者信息

Gupta Sahil, Gupta Arjun, Saini Ashish K, Majumder Kaustav, Sinha Kalpana, Chahal Anurag

机构信息

All India Institute of Medical Sciences, New Delhi, India.

UT Southwestern Medical Center, Dallas, Tex, M.N., USA.

出版信息

Curr Urol. 2017 Jan;9(4):212-215. doi: 10.1159/000447143. Epub 2016 Dec 26.

Abstract

Prostate cancer is the most common non-cutaneous malignancy in men. It is generally considered a cancer of the elderly, and the median age of presentation is 68 years. However 10% of new diagnoses in the USA occur in men aged ≤ 55 years. This may be due to more prevalent screening nowadays, and may also reflect the diagnosis of an increasingly recognized but underappreciated entity, i.e. early-onset prostate cancer. Patients with early onset prostate cancer pose unique challenges. Current data suggest that early-onset prostate cancer is a distinct phenotype-from both an etiological and clinical perspective- that deserves further attention. We present a case of a 28-year-old man who presented with lower urinary tract symptoms and was diagnosed with advanced stage prostate cancer.

摘要

前列腺癌是男性最常见的非皮肤恶性肿瘤。它通常被认为是一种老年癌症,确诊时的中位年龄为68岁。然而,在美国,10%的新确诊病例发生在年龄≤55岁的男性中。这可能是由于如今筛查更为普遍,也可能反映出一种越来越被认识到但未得到充分重视的疾病实体的诊断,即早发性前列腺癌。早发性前列腺癌患者带来了独特的挑战。目前的数据表明,从病因学和临床角度来看,早发性前列腺癌是一种独特的表型,值得进一步关注。我们报告一例28岁男性患者,他因下尿路症状就诊,被诊断为晚期前列腺癌。

相似文献

1
Prostate Cancer: How Young is too Young?前列腺癌:多年轻算太年轻?
Curr Urol. 2017 Jan;9(4):212-215. doi: 10.1159/000447143. Epub 2016 Dec 26.
3
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Current clinical challenges in prostate cancer.前列腺癌当前的临床挑战。
Transl Androl Urol. 2013 Sep;2(3):122-36. doi: 10.3978/j.issn.2223-4683.2013.09.03.

引用本文的文献

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Early onset prostate cancer has a significant genetic component.早期前列腺癌有显著的遗传因素。
Prostate. 2012 Feb 1;72(2):147-56. doi: 10.1002/pros.21414. Epub 2011 May 2.
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The prognosis of prostatic cancer in the younger man.年轻男性前列腺癌的预后
Br J Urol. 1983 Jun;55(3):315-20. doi: 10.1111/j.1464-410x.1983.tb03307.x.

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