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本文引用的文献

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Quantifying stochastic uncertainty and presenting results of cost-effectiveness analyses.量化随机不确定性并呈现成本效益分析结果。
Expert Rev Pharmacoecon Outcomes Res. 2001 Oct;1(1):25-36. doi: 10.1586/14737167.1.1.25.
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Randomised controlled trial of a short course of traditional acupuncture compared with usual care for persistent non-specific low back pain.与常规护理相比,传统针灸短疗程治疗持续性非特异性腰痛的随机对照试验。
BMJ. 2006 Sep 23;333(7569):623. doi: 10.1136/bmj.38878.907361.7C. Epub 2006 Sep 15.
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Handling missing data in patient-level cost-effectiveness analysis alongside randomised clinical trials.在患者层面的成本效益分析中与随机临床试验一起处理缺失数据。
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Pragmatic clinical trials.实用临床试验。
Complement Ther Med. 2004 Jun-Sep;12(2-3):136-40. doi: 10.1016/j.ctim.2004.07.043.
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United Kingdom back pain exercise and manipulation (UK BEAM) randomised trial: cost effectiveness of physical treatments for back pain in primary care.英国背痛锻炼与手法治疗(UK BEAM)随机试验:基层医疗中背痛物理治疗的成本效益
BMJ. 2004 Dec 11;329(7479):1381. doi: 10.1136/bmj.38282.607859.AE. Epub 2004 Nov 19.
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Randomised controlled trial of physiotherapy compared with advice for low back pain.物理治疗与腰痛建议对比的随机对照试验
BMJ. 2004 Sep 25;329(7468):708. doi: 10.1136/bmj.38216.868808.7C. Epub 2004 Sep 17.
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Cost effectiveness analysis of a randomised trial of acupuncture for chronic headache in primary care.一项关于初级保健中针刺治疗慢性头痛的随机试验的成本效益分析。
BMJ. 2004 Mar 27;328(7442):747. doi: 10.1136/bmj.38033.896505.EB. Epub 2004 Mar 15.
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The estimation of a preference-based measure of health from the SF-36.基于SF-36量表对健康偏好测量值的估计。
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Is acupuncture effective for the treatment of chronic pain? A systematic review.针灸对慢性疼痛的治疗有效吗?一项系统评价。
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针刺疗法治疗持续性腰痛的随机对照试验:成本效益分析

A randomised controlled trial of acupuncture care for persistent low back pain: cost effectiveness analysis.

作者信息

Ratcliffe J, Thomas K J, MacPherson H, Brazier J

机构信息

School of Health and Related Research, University of Sheffield.

出版信息

BMJ. 2006 Sep 23;333(7569):626. doi: 10.1136/bmj.38932.806134.7C. Epub 2006 Sep 15.

DOI:10.1136/bmj.38932.806134.7C
PMID:16980315
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1570795/
Abstract

OBJECTIVE

To evaluate the cost effectiveness of acupuncture in the management of persistent non-specific low back pain.

DESIGN

Cost effectiveness analysis of a randomised controlled trial.

SETTING

Three private acupuncture clinics and 18 general practices in York, England.

PARTICIPANTS

241 adults aged 18-65 with non-specific low back pain of 4-52 weeks' duration.

INTERVENTIONS

Ten individualised acupuncture treatments over three months from acupuncturists trained in traditional Chinese medicine (n = 160) or usual care only (n = 81).

MAIN OUTCOME MEASURE

Incremental cost per quality adjusted life year (QALY) gained over two years.

RESULTS

Total costs to the United Kingdom's health service during the two year study period were higher on average for the acupuncture group (460 pounds sterling; 673 euros; 859 dollars) than for the usual care group (345 pounds sterling) because of the costs associated with initial treatment. The mean incremental health gain from acupuncture at 12 months was 0.012 QALYs (95% confidence interval -0.033 to 0.058) and at 24 months was 0.027 QALYs (-0.056 to 0.110), leading to a base case estimate of 4241 pounds sterling per QALY gained. This result was robust to sensitivity analysis. The probabilistic sensitivity analysis showed acupuncture to have a more than 90% chance of being cost effective at a pound20 000 cost per QALY threshold.

CONCLUSION

A short course of traditional acupuncture for persistent non-specific low back pain in primary care confers a modest health benefit for minor extra cost to the NHS compared with usual care. Acupuncture care for low back pain seems to be cost effective in the longer term.

TRIAL REGISTRATION

ISRCTN80764175 [controlled-trials.com].

摘要

目的

评估针刺疗法治疗持续性非特异性下腰痛的成本效益。

设计

一项随机对照试验的成本效益分析。

地点

英国约克郡的三家私人针灸诊所和18家普通诊所。

参与者

241名年龄在18至65岁之间、患有持续4至52周非特异性下腰痛的成年人。

干预措施

接受由受过中医培训的针灸师进行的为期三个月的十次个体化针刺治疗(n = 160)或仅接受常规护理(n = 81)。

主要结局指标

两年内每获得一个质量调整生命年(QALY)的增量成本。

结果

在为期两年的研究期间,由于初始治疗相关成本,针刺组英国国民医疗服务体系(NHS)的总成本平均(460英镑;673欧元;859美元)高于常规护理组(345英镑)。针刺疗法在12个月时的平均增量健康收益为0.012个QALY(95%置信区间为-0.033至0.058),在24个月时为0.027个QALY(-0.056至0.110),得出每获得一个QALY的基础病例估计成本为4241英镑。该结果对敏感性分析具有稳健性。概率敏感性分析表明,在每QALY阈值成本为20000英镑时,针刺疗法具有超过90%的成本效益可能性。

结论

与常规护理相比,在初级保健中对持续性非特异性下腰痛进行短期的传统针刺治疗,可为NHS带来适度的健康益处,但成本略有增加。从长远来看,针刺疗法治疗下腰痛似乎具有成本效益。

试验注册

ISRCTN80764175 [controlled-trials.com]