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骨传导刺激诱发前庭诱发肌源性电位的初步研究

Preliminary study on vestibular-evoked myogenic potential induced by bone-conducted stimuli.

作者信息

Miyamoto Atsushi, Seo Toru, Node Michiko, Hashimoto Misako, Sakagami Masafumi

机构信息

Department of Otolaryngology, Hyogo College of Medicine, Nishinomiya, Japan.

出版信息

Otol Neurotol. 2006 Dec;27(8):1110-4. doi: 10.1097/01.mao.0000231599.33585.c6.

DOI:10.1097/01.mao.0000231599.33585.c6
PMID:16980915
Abstract

OBJECTIVE

To study the relationship between vestibular-evoked myogenic potential evoked by air-conducted stimuli (A-VEMP) and those evoked by bone-conducted stimuli (B-VEMP).

STUDY DESIGN

Prospective study.

SETTING

University Hospital.

PATIENTS

To determine the optimum stimulus conditions for B-VEMP, 40 ears of 20 healthy volunteers were used. To compare results of A-VEMP and B-VEMP, 60 ears of 30 healthy volunteers and 70 ears of 35 patients with unilateral vestibular disorder without conductive hearing loss were used.

MAIN OUTCOME MEASURE

A-VEMP and B-VEMP were measured. Both examinations involved evaluation of the interaural ratio (IAR) of the p13-n23 peak-to-peak amplitude. To compare the relationship between A-VEMP and B-VEMP in healthy subjects and patients with unilateral vestibular disorder.

RESULTS

The optimum stimulus for B-VEMP seemed to be a tone-burst sound with 8-ms duration at 250 Hz. In all healthy subjects, both A-VEMP and B-VEMP could be recorded. The mean IAR of B-VEMP (0.5 +/- 21.0%) was not significantly different from that of A-VEMP (0.2 +/- 19.4%). In patients with unilateral vestibular disorder, B-VEMP could not be detected in 10 ears in which A-VEMP also could not be detected. The IAR of A-VEMP was strongly correlated with that of B-VEMP (correlation coefficient, 0.98).

CONCLUSION

The results of B-VEMP were almost the same as those for A-VEMP, at least, for patients without conductive hearing loss.

摘要

目的

研究气导刺激诱发的前庭诱发肌源性电位(A-VEMP)与骨导刺激诱发的前庭诱发肌源性电位(B-VEMP)之间的关系。

研究设计

前瞻性研究。

研究地点

大学医院。

患者

为确定B-VEMP的最佳刺激条件,使用了20名健康志愿者的40只耳。为比较A-VEMP和B-VEMP的结果,使用了30名健康志愿者的60只耳以及35名单侧前庭疾病且无传导性听力损失患者的70只耳。

主要观察指标

测量A-VEMP和B-VEMP。两项检查均涉及评估p13-n23峰峰值振幅的双耳比率(IAR)。比较健康受试者和单侧前庭疾病患者中A-VEMP与B-VEMP之间的关系。

结果

B-VEMP的最佳刺激似乎是250Hz、持续时间8ms的短纯音。在所有健康受试者中,均可记录到A-VEMP和B-VEMP。B-VEMP的平均IAR(0.5±21.0%)与A-VEMP的平均IAR(0.2±19.4%)无显著差异。在单侧前庭疾病患者中,10只耳未检测到B-VEMP,这些耳中A-VEMP也未检测到。A-VEMP的IAR与B-VEMP的IAR高度相关(相关系数为0.98)。

结论

至少对于无传导性听力损失的患者,B-VEMP的结果与A-VEMP的结果几乎相同。

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