Positively coded photoaffinity label for altering isoelectric points of proteins.
作者信息
Hashimoto Makoto, Hatanaka Yasumaru
机构信息
Department of Agricultural and Life Science, Obihiro University of Agriculture and Veterinary Medicine, Inada-cho, Obihiro, Hokkaido 080-8555, Japan.
出版信息
Bioorg Med Chem Lett. 2006 Dec 1;16(23):5998-6000. doi: 10.1016/j.bmcl.2006.08.119. Epub 2006 Sep 18.
PMID:16982189
Abstract
Novel diazirinyl photoaffinity ligand, which contains (3-trifluoromethyl) phenyldiazirine and penta(epsilon-Boc-Lys) as a photoreactive code, allows the introduction of a positive cascade to alter the pI value of labeled components, facilitating the isolation of photolabeled biocomponents with isoelectric focusing techniques.
摘要
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