Davis Anne R, Osborne Lauren M, O'Connell Katharine J, Westhoff Carolyn L
Department of Obstetrics and Gynecology, Columbia University, New York, New York 10032, USA.
J Adolesc Health. 2006 Oct;39(4):607-9. doi: 10.1016/j.jadohealth.2006.03.019. Epub 2006 Jul 10.
We recruited adolescents to study oral contraceptives versus placebo for dysmenorrhea. We anticipated high discontinuation and concerns about safety, side effects, and sexual behavior. Treatment discontinuation (11%) and loss to follow-up (1%) were lower than expected. The most common reason for nonenrollment was logistical issues (63%). Most participants remained abstinent.
我们招募青少年来研究口服避孕药与安慰剂治疗痛经的效果。我们预计会有较高的停药率以及对安全性、副作用和性行为的担忧。治疗停药率（11%）和失访率（1%）低于预期。未入组的最常见原因是后勤问题（63%）。大多数参与者保持禁欲。
