Armstrong David G, Lavery Lawrence A, Frykberg Robert G, Wu Stephanie C, Boulton Andrew J M
Scholl's Center for Lower Extremity Ambulatory Research at Rosalind Franklin University of Medicine and Science, North Chicago, IL 60064, USA.
Int Wound J. 2006 Sep;3(3):240-6. doi: 10.1111/j.1742-481X.2006.00236.x.
The purpose of this project was to evaluate associations of increasing diabetic foot surgery stage with postoperative outcome. This project, designed as a retrospective cohort model, was conducted at three large, urban referral-based diabetic foot clinics. The investigators abstracted medical records from 180 patients with diabetes, 76.1% male, aged 57.8 +/- 11.2 years, falling equally into four classes of a previously reported diabetic foot surgery classification system. These classes included class 1 (elective), class 2 (prophylactic), class 3 (curative) and class 4 (emergency). There was a significant trend towards increasing risk of ulceration/reulceration (chi2(trend) = 17.8, P = 0.0001), peri-postoperative infection (chi2(trend) = 96.9, P = 0.0001), all-level amputation (chi2(trend) = 41.7, P = 0.001) and major amputation (chi2(trend) = 8.6, P = 0.003), with increasing class of foot surgery. The results of this study suggest that a non vascular foot surgery classification system including variables such as the presence or absence of neuropathy, an open wound and acute infection may be predictive of peri- and postoperative complications. This may assist the surgeon in better identifying risk when determining a rationale for and type of surgery in persons with diabetes.
本项目旨在评估糖尿病足手术分期增加与术后结局之间的关联。本项目设计为回顾性队列模型,在三家大型城市转诊型糖尿病足诊所开展。研究人员从180例糖尿病患者中提取医疗记录,患者男性占76.1%,年龄为57.8±11.2岁,平均分为先前报道的糖尿病足手术分类系统的四个类别。这些类别包括1类(择期)、2类(预防性)、3类(根治性)和4类(急诊)。随着足部手术类别的增加,溃疡/再溃疡风险增加(趋势χ2=17.8,P=0.0001)、围手术期感染(趋势χ2=96.9,P=0.0001)、各级截肢(趋势χ2=41.7,P=0.001)和大截肢(趋势χ2=8.6,P=0.003)均有显著趋势。本研究结果表明,一个包括神经病变、开放性伤口和急性感染等变量的非血管性足部手术分类系统可能有助于预测围手术期和术后并发症。这可能有助于外科医生在确定糖尿病患者的手术理由和手术类型时更好地识别风险。