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韩国肠易激综合征的患病率:基于罗马II标准的人群调查

Prevalence of irritable bowel syndrome in Korea: population-based survey using the Rome II criteria.

作者信息

Han Sung Hee, Lee Oh Young, Bae Sang Cheol, Lee Seok Hwa, Chang Yu Kyung, Yang Sun Young, Yoon Byung Chul, Choi Ho Soon, Hahm Joon Soo, Lee Min Ho, Lee Dong Hoo, Kim Tae Hwa

机构信息

Department of Internal Medicine, College of Medicine, Hanyang University, Seoul, Korea.

出版信息

J Gastroenterol Hepatol. 2006 Nov;21(11):1687-92. doi: 10.1111/j.1440-1746.2006.04269.x.

DOI:10.1111/j.1440-1746.2006.04269.x
PMID:16984590
Abstract

BACKGROUND

Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder in the West. But information on the prevalence of IBS in Asia is still lacking, especially in Korea. Therefore, the aims of the present study were to estimate the prevalence of IBS in the general population of Korea and also to investigate characteristics of IBS and health-care-seeking behavior of IBS patients.

METHODS

Telephone interview survey was conducted by Gallup, Korea using a validated questionnaire based on the Rome II criteria. The response rate of the telephone interview survey was 25.2% (n = 1066, 535 male and 531 female responders). A random sample of gender and age (between 18 and 60 years), based on a per capita ratio was obtained.

RESULTS

Among 1066 subjects, the prevalence of IBS was 6.6% (70 subjects; 7.1%, male; 6.0%, female). The difference in IBS prevalence by gender was not significant. The prevalence was higher among those in their 20s (P = 0.036). Among 70 subjects with IBS, 10/20 IBS subjects sought health care due to abdominal pain. Among the risk factors of IBS, marital status had a significant difference; the following risk factors are arranged in descending order: age (odds ratio [OR]: 1.38, 95% confidence interval [CI]: 0.85-2.25), alcohol intake (OR: 1.38, 95%CI: 0.81-2.35), gender (OR: 1.19, 95%CI: 0.73-1.94), demographics (OR: 1.09, 95%CI: 0.53-2.25), income (OR: 0.88, 95%CI: 0.54-1.45), education level (OR: 0.81, 95%CI: 0.46-1.40), smoking (OR: 0.64, 95%CI: 0.37-1.12), and marital status (OR: 0.59, 95%CI: 0.35-0.99).

CONCLUSIONS

The prevalence of IBS in the Korean population is 6.6%, and the male:female ratio is similar. Also, IBS is more frequent in younger subjects. Irritable bowel syndrome subjects visited a physician mostly due to abdominal pain.

摘要

背景

肠易激综合征(IBS)在西方是一种常见的功能性胃肠疾病。但亚洲关于IBS患病率的信息仍然匮乏,尤其是在韩国。因此,本研究的目的是估计韩国普通人群中IBS的患病率,并调查IBS的特征以及IBS患者的就医行为。

方法

韩国盖洛普公司使用基于罗马II标准的有效问卷进行电话访谈调查。电话访谈调查的回复率为25.2%(n = 1066,535名男性和531名女性受访者)。基于人均比例获得了按性别和年龄(18至60岁)分层的随机样本。

结果

在1066名受试者中,IBS的患病率为6.6%(70名受试者;男性为7.1%,女性为6.0%)。IBS患病率的性别差异不显著。20多岁人群中的患病率更高(P = 0.036)。在70名IBS受试者中,10/20的IBS受试者因腹痛寻求医疗护理。在IBS的风险因素中,婚姻状况有显著差异;以下风险因素按降序排列:年龄(比值比[OR]:1.38,95%置信区间[CI]:0.85 - 2.25)、饮酒(OR:1.38,95%CI:0.81 - 2.35)、性别(OR:1.19,95%CI:0.73 - 1.94)、人口统计学特征(OR:1.09,95%CI:0.53 - 2.25)、收入(OR:0.88,95%CI:0.54 - 1.45)、教育水平(OR:0.81,95%CI:0.46 - 1.40)、吸烟(OR:0.64,95%CI:0.37 - 1.12)和婚姻状况(OR:0.59,95%CI:0.35 - 0.99)。

结论

韩国人群中IBS的患病率为6.6%,男女比例相似。此外,IBS在年轻受试者中更为常见。肠易激综合征受试者大多因腹痛就诊。

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