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用于治疗小动物内分泌疾病的药物最新进展。

Update on drugs used to treat endocrine diseases in small animals.

作者信息

Behrend Ellen N

机构信息

Department of Clinical Sciences, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA.

出版信息

Vet Clin North Am Small Anim Pract. 2006 Sep;36(5):1087-105, vii. doi: 10.1016/j.cvsm.2006.05.007.

DOI:10.1016/j.cvsm.2006.05.007
PMID:16984828
Abstract

Drug therapy for the endocrine system is implemented to replace a hormone deficiency or to prevent or reduce the formation or effects of excess hormone. Treatment of endocrine disorders covers diseases of the pituitary, adrenal, parathyroid, and thyroid glands as well as the endocrine pancreas. This article focuses on new therapies currently available for specific diseases. Administration of trilostane for treatment of hyperadrenocorticism and use of insulin glargine, protamine zinc insulin (PZI), and porcine Lente insulin for diabetes mellitus are discussed. In addition, transdermal methimazole therapy for treatment of feline hyperthyroidism and administration of progestins for pituitary dwarfism are considered.

摘要

内分泌系统的药物治疗旨在补充激素缺乏,或预防或减少过量激素的形成及其影响。内分泌疾病的治疗涵盖垂体、肾上腺、甲状旁腺、甲状腺以及内分泌胰腺的疾病。本文重点介绍目前可用于特定疾病的新疗法。讨论了使用曲洛司坦治疗肾上腺皮质功能亢进,以及使用甘精胰岛素、精蛋白锌胰岛素(PZI)和猪低精蛋白胰岛素治疗糖尿病。此外,还考虑了使用透皮甲巯咪唑治疗猫甲状腺功能亢进,以及使用孕激素治疗垂体性侏儒症。

相似文献

1
Update on drugs used to treat endocrine diseases in small animals.用于治疗小动物内分泌疾病的药物最新进展。
Vet Clin North Am Small Anim Pract. 2006 Sep;36(5):1087-105, vii. doi: 10.1016/j.cvsm.2006.05.007.
2
Retrospective evaluation of the effect of trilostane on insulin requirement and fructosamine concentration in eight diabetic dogs with hyperadrenocorticism.曲洛司坦对8只患有肾上腺皮质功能亢进的糖尿病犬胰岛素需求量和果糖胺浓度影响的回顾性评估。
J Small Anim Pract. 2010 Dec;51(12):642-8. doi: 10.1111/j.1748-5827.2010.01005.x.
3
Trilostane in dogs.曲洛司坦在犬类中的应用。
Vet Clin North Am Small Anim Pract. 2010 Mar;40(2):269-83. doi: 10.1016/j.cvsm.2009.10.008.
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Trilostane therapy for treatment of pituitary-dependent hyperadrenocorticism in 5 cats.曲洛司坦治疗5只猫垂体依赖性肾上腺皮质功能亢进症
J Vet Intern Med. 2004 Mar-Apr;18(2):160-4. doi: 10.1892/0891-6640(2004)18<160:ttftop>2.0.co;2.
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The effect of trilostane treatment on circulating thyroid hormone concentrations in dogs with pituitary-dependent hyperadrenocorticism.曲洛司坦治疗对垂体依赖性肾上腺皮质功能亢进犬循环甲状腺激素浓度的影响。
J Small Anim Pract. 2008 Mar;49(3):139-43. doi: 10.1111/j.1748-5827.2007.00509.x. Epub 2007 Dec 18.
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Preliminary study of protamine zinc recombinant insulin for the treatment of diabetes mellitus in cats.精蛋白锌重组胰岛素治疗猫糖尿病的初步研究。
Vet Ther. 2009 Spring-Summer;10(1-2):24-8.
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Pharmacologic management of feline hyperthyroidism.猫甲状腺功能亢进的药物治疗
Vet Clin North Am Small Anim Pract. 2007 Jul;37(4):775-88, vii. doi: 10.1016/j.cvsm.2007.03.004.
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Hyperadrenocorticism: treating dogs.肾上腺皮质功能亢进:犬类治疗
Compend Contin Educ Vet. 2007 Mar;29(3):132-4, 136, 138 passim; quiz 144-5.
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Effect of lente insulin for treatment of diabetes mellitus in 12 cats.长效胰岛素对12只猫糖尿病的治疗效果。
J Am Vet Med Assoc. 1995 Jun 1;206(11):1729-31.
10
Adrenocorticotropic hormone levels in dogs with pituitary-dependent hyperadrenocorticism following trilostane therapy.曲洛司坦治疗后垂体依赖性肾上腺皮质功能亢进犬的促肾上腺皮质激素水平
Vet Rec. 2004 Mar 27;154(13):399-400. doi: 10.1136/vr.154.13.399.

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