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用于治疗小动物内分泌疾病的药物最新进展。

Update on drugs used to treat endocrine diseases in small animals.

作者信息

Behrend Ellen N

机构信息

Department of Clinical Sciences, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA.

出版信息

Vet Clin North Am Small Anim Pract. 2006 Sep;36(5):1087-105, vii. doi: 10.1016/j.cvsm.2006.05.007.

Abstract

Drug therapy for the endocrine system is implemented to replace a hormone deficiency or to prevent or reduce the formation or effects of excess hormone. Treatment of endocrine disorders covers diseases of the pituitary, adrenal, parathyroid, and thyroid glands as well as the endocrine pancreas. This article focuses on new therapies currently available for specific diseases. Administration of trilostane for treatment of hyperadrenocorticism and use of insulin glargine, protamine zinc insulin (PZI), and porcine Lente insulin for diabetes mellitus are discussed. In addition, transdermal methimazole therapy for treatment of feline hyperthyroidism and administration of progestins for pituitary dwarfism are considered.

摘要

内分泌系统的药物治疗旨在补充激素缺乏,或预防或减少过量激素的形成及其影响。内分泌疾病的治疗涵盖垂体、肾上腺、甲状旁腺、甲状腺以及内分泌胰腺的疾病。本文重点介绍目前可用于特定疾病的新疗法。讨论了使用曲洛司坦治疗肾上腺皮质功能亢进,以及使用甘精胰岛素、精蛋白锌胰岛素(PZI)和猪低精蛋白胰岛素治疗糖尿病。此外,还考虑了使用透皮甲巯咪唑治疗猫甲状腺功能亢进,以及使用孕激素治疗垂体性侏儒症。

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