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前列腺癌病理学、筛查与流行病学

Prostate cancer pathology, screening, and epidemiology.

作者信息

Crawford E D, Miller G J, Labrie F, Hirano D, Batuello J, Glodé L M

出版信息

Rev Urol. 2001;3 Suppl 2(Suppl 2):S2-S10.

Abstract

Recent advances in the understanding of prostate cancer pathology, screening methods, and epidemiology were discussed at the 11th International Prostate Cancer Update. Regarding pathology, Dr. Gary Miller enumerated several factors that lead to the perception of prostate cancer as "unpredictable." These include the disease's multifocal nature, variable progression rates, and the uncertainty regarding the point at which carcinomas metastasize. Screening methods have been the subject of research by the Laval University Prostate Cancer Screening Program since 1988. Dr. Fernand Labrie presented the results of this 10-year study. Dr. Daisaku Hirano presented data from his studies of prostate cancer epidemiology in Japan as compared to the United States. The role of environmental factors, particularly diet, in prostate cancer pathogenesis and development is supported by the increase of the disease in Japan, concurrent with the "westernization" of diet there. Finally, useful information was presented on new computer- and Internet-based diagnostic and research tools.

摘要

在第11届国际前列腺癌最新进展研讨会上,人们讨论了前列腺癌病理学、筛查方法和流行病学方面的最新进展。关于病理学,加里·米勒博士列举了几个导致前列腺癌被视为“不可预测”的因素。这些因素包括该疾病的多灶性、不同的进展速度以及癌症转移时间的不确定性。自1988年以来,拉瓦尔大学前列腺癌筛查项目一直在研究筛查方法。费尔南德·拉布里博士介绍了这项为期10年研究的结果。平野大作博士展示了他对日本与美国前列腺癌流行病学研究的数据。日本前列腺癌发病率随着饮食的“西化”而上升,这支持了环境因素,尤其是饮食,在前列腺癌发病机制和发展中的作用。最后,会上介绍了基于计算机和互联网的新型诊断和研究工具的有用信息。

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