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前列腺癌的补充医学:大豆和脂肪摄入的影响。

Complementary medicine for prostate cancer: effects of soy and fat consumption.

作者信息

Moyad M A, Sakr W A, Hirano D, Miller G J

出版信息

Rev Urol. 2001;3 Suppl 2(Suppl 2):S20-30.

Abstract

Complementary medicine has become an increasing area of interest for patients and researchers around the world. The utilization of some of these therapies by many individuals makes it imperative to understand if they have a role in cancer or other disease treatment. Soy products have generated a large interest because a variety of laboratory and epidemiologic research suggests these items may play a role in the prevention of prostate cancer. Clinical trials are addressing this issue and whether or not these products could also improve prognosis of prostate cancer. Additionally, other soy-based capsules (ipriflavone) have received some research, but the largest clinical study to date does not support the use of these supplements to reduce hot flashes and/or osteoporosis risk. Dietary fat reduction to prevent prostate cancer is supported by numerous case-control studies over the past 25 years. However, recent prospective studies suggest that fat reduction may not play a strong role in prevention of prostate carcinoma. Soy products and fat reduction may have a symbiotic relationship. Any healthy lifestyle or dietary change should be encouraged, because it may reduce the risk of cardiovascular disease, which is still the number one cause of mortality.

摘要

补充医学已成为全球患者和研究人员日益关注的领域。许多人对其中一些疗法的使用使得了解它们在癌症或其他疾病治疗中是否发挥作用变得势在必行。大豆制品引发了广泛关注,因为各种实验室和流行病学研究表明,这些产品可能在预防前列腺癌方面发挥作用。临床试验正在探讨这个问题,以及这些产品是否还能改善前列腺癌的预后。此外,其他大豆基胶囊(异黄酮)也受到了一些研究,但迄今为止最大的临床研究并不支持使用这些补充剂来降低潮热和/或骨质疏松症风险。过去25年中,大量病例对照研究支持通过减少膳食脂肪来预防前列腺癌。然而,最近的前瞻性研究表明,减少脂肪摄入在预防前列腺癌方面可能作用不大。大豆制品和减少脂肪摄入可能存在共生关系。任何健康的生活方式或饮食改变都应得到鼓励,因为这可能降低心血管疾病的风险,而心血管疾病仍是头号死因。

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本文引用的文献

2
CIRRHOSIS AND CARCINOMA OF THE PROSTATE GLAND.前列腺肝硬化与癌
J Urol. 1964 Mar;91:291-3. doi: 10.1016/S0022-5347(17)64110-7.

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