Mikhaleva L M, Vorob'eva N N, Samsonova M V
Arkh Patol. 2006 Jul-Aug;68(4):20-2.
Glandular cystic ovarian endometriosis (OE) is characterized by a more intensive blood supply than cystic OE. This type of OE is characterized by a high proliferative glandular epithelial activity detected by an immunohistochemical study using antibodies to PCNA and CA-125. Moreover, a positive correlation is found between the serum concentration of CA-125 and the expression of this antigen in the epitheliocytes of an endometrioid cyst in both glandular-cystic and cystic OE. Thus, the findings permit the determination of the morphofunctional activity of a type of OE and its aptness to the progression of the disease and to the development of recurrences.
腺囊性卵巢子宫内膜异位症(OE)的特征是其血供比囊性OE更为丰富。这种类型的OE的特点是,通过使用抗增殖细胞核抗原(PCNA)和癌抗原125(CA-125)抗体进行免疫组织化学研究检测到高增殖性腺上皮活性。此外,在腺囊性和囊性OE中,均发现CA-125血清浓度与子宫内膜样囊肿上皮细胞中该抗原的表达之间存在正相关。因此,这些发现有助于确定一种OE的形态功能活性及其疾病进展和复发的倾向。