海利螺内酯B和C：两种具有新型螺杂环倍半萜骨架的新型植物海利螺烷。

Heliespirones B and C: two new plant heliespiranes with a novel spiro heterocyclic sesquiterpene skeleton.

作者信息

Macías Francisco A, Galindo José L G, Varela Rosa M, Torres Ascensión, Molinillo José M G, Fronczek Frank R

机构信息

Grupo de Alelopatía, Departamento de Química Organica, Universidad de Cadiz, Facultad de Ciencias, C/República Saharaui s/n, 11510 Puerto Real, Cadiz, Spain.

出版信息

Org Lett. 2006 Sep 28;8(20):4513-6. doi: 10.1021/ol061673a.

DOI:10.1021/ol061673a

PMID:16986938

Abstract

From the medium, polar bioactive fractions of leaf aqueous extract of Helianthus annuus L., heliespirones B (2) and C (3) have been isolated. The structural elucidation was based on extensive spectral studies. A probable biogenesis of heliespirone skeleton is proposed and discussed. The structure of heliespirone B has been confirmed by X-ray diffraction analysis.

摘要

从向日葵叶水提取物的中等极性生物活性组分中，分离得到了向日葵螺环酮B（2）和C（3）。结构解析基于广泛的光谱研究。提出并讨论了向日葵螺环酮骨架可能的生物合成途径。向日葵螺环酮B的结构已通过X射线衍射分析得到证实。