Van Howe R S, Hodges F M
Department of Pediatrics, Michigan State University School of Human Medicine, Marquette, MI, USA.
J Eur Acad Dermatol Venereol. 2006 Oct;20(9):1046-54. doi: 10.1111/j.1468-3083.2006.01653.x.
Smegma is widely believed to cause penile, cervical and prostate cancer. This nearly ubiquitous myth continues to permeate the medical literature despite a lack of valid supportive evidence.
A historical perspective of medical ideas pertaining to smegma is provided, and the original studies in both animals and humans are reanalysed using the appropriate statistical methods.
Evidence supporting the role of smegma as a carcinogen is found wanting.
Assertions that smegma is carcinogenic cannot be justified on scientific grounds.
人们普遍认为包皮垢会引发阴茎癌、宫颈癌和前列腺癌。尽管缺乏有效的支持证据，但这个几乎无处不在的错误观念仍持续出现在医学文献中。
本文提供了关于包皮垢医学观点的历史视角，并运用适当的统计方法对动物和人类的原始研究进行重新分析。
支持包皮垢作为致癌物作用的证据不足。
关于包皮垢具有致癌性的断言在科学上是站不住脚的。
