Moshchin'ski P, Slovin'ski S, Moshchin'ski P, Zhabuvka M
Lab Delo. 1990(6):57-60.
B-lymphocyte counts, immunoglobulin levels, blood serum antiA and antiB isoagglutinin concentrations and lysozyme activity, and hemolytic activity of the complement were measured in 85 healthy men aged 18 to 42 (mean age 34) smoking 15-25 cigarettes daily for 2-25 years and in a reference group of 49 nonsmokers aged 17 to 50 (mean age 31). Tobacco smoking was found to have no effect on the peripheral blood B lymphocyte count, nor on the blood serum concentrations of group isoagglutinins. In men smoking for 6.5 years on an average the absolute count of lymphocytes was elevated vs. the reference value. In those smoking for 18.5 years on an average IgA, IgG, and lysozyme concentrations were lowered. These results evidence that the mechanism of humoral immunity weakening in tobacco smokers is intricate and related to a deficit of many proteins responsible for immunobiological processes in human body.
对85名年龄在18至42岁（平均年龄34岁）、每天吸烟15 - 25支、烟龄2至25年的健康男性，以及49名年龄在17至50岁（平均年龄31岁）的非吸烟对照者，检测了B淋巴细胞计数、免疫球蛋白水平、血清抗A和抗B同种凝集素浓度、溶菌酶活性以及补体的溶血活性。结果发现，吸烟对外周血B淋巴细胞计数以及血清同种凝集素浓度均无影响。平均吸烟6.5年的男性，淋巴细胞绝对计数相对于参考值升高。平均吸烟18.5年的男性，IgA、IgG和溶菌酶浓度降低。这些结果表明，吸烟者体液免疫减弱的机制复杂，且与人体免疫生物学过程中多种蛋白质的缺乏有关。
