Ahluwalia Monica, Light Anton Michael, Surampudi K, Finn Catherine B
Department of Cellular Pathology, Good Hope Hospital, Sutton Coldfield, West Midlands, B75 7RR, UK.
Int J Gynecol Pathol. 2006 Oct;25(4):378-82. doi: 10.1097/01.pgp.0000215296.53361.4b.
We report a case of primary transitional cell carcinoma of the endometrium and review the literature which reveals only 12 cases described to date. The patient presented with postmenopausal bleeding, and there were no distinctive clinical features. An endometrial sample taken at hysteroscopy was reported as a poorly differentiated, papillary, nonserous carcinoma with probable squamous metaplasia. The tumor removed at hysterectomy and bilateral salpingo-oophorectomy was almost all transitional cell with small areas of endometrioid, glandular differentiation. Immunohistochemistry demonstrated a similar immunoprofile to endometrioid carcinoma of the endometrium and different from reported cases of transitional cell carcinoma of the ovary and of the urinary tract.
我们报告一例原发性子宫内膜移行细胞癌，并回顾相关文献，发现迄今为止仅有12例相关病例报道。该患者表现为绝经后出血，无明显临床特征。宫腔镜检查时获取的子宫内膜样本报告为低分化、乳头状、非浆液性癌，可能伴有鳞状化生。子宫切除及双侧输卵管卵巢切除术后切除的肿瘤几乎全为移行细胞，伴有小面积子宫内膜样腺性分化区域。免疫组化显示其免疫表型与子宫内膜样腺癌相似，与报道的卵巢及泌尿道移行细胞癌病例不同。
