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[拉沙病毒在近交系小鼠体内的干扰素诱导活性]

[The interferon-inducing activity of the Lassa virus in the body of inbred mice].

作者信息

Zudin B I, Rozdialovskiĭ A N, Petkevich A S

出版信息

Vopr Virusol. 1990 May-Jun;35(3):231-3.

PMID:1699360
Abstract

The level and the time course of accumulation of endogenous interferon were studied in the blood sera of mice experimentally infected with Lassa virus by the intracerebral route. The level of interferon correlated with case-fatality rate of the animals which may be important for the understanding of the pathogenesis of arenavirus infections.

摘要

通过脑内途径用拉沙病毒实验性感染小鼠,研究了其血清中内源性干扰素的积累水平和时间进程。干扰素水平与动物的病死率相关,这对于理解沙粒病毒感染的发病机制可能很重要。

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