Hörmann K, Bernal Sprekelsen M
Departamento de O.R.L. Hospital General de Kaiserlautern/R.F.A.
An Otorrinolaringol Ibero Am. 1990;17(4):397-404.
The aim of the rheological treatment in sudden deafness is the improvement of the microcirculation in the inner ear by hemodilution and decreased viscosity of the blood. Both parameters have been checked in two groups of patients suffering from sudden deafness; one treated with Dextran-40 and Pentoxifylline, the other with Dextran-40 only. Improvement of rheological characteristics of blood was statistically significant in the combined therapy with Dextran-40 and Pentoxifylline. Two cohorts of sudden deafness patients--one selected, one non selected--treated with Pentoxifylline and Dextran 40 have been evaluated in respect of hearing improvement under this rheological results compared with the spontaneous remission rate given by Weinaug in 1984.
突发性耳聋的流变学治疗目的是通过血液稀释和降低血液粘度来改善内耳的微循环。这两个参数已在两组突发性耳聋患者中进行了检查；一组用低分子右旋糖酐-40和己酮可可碱治疗，另一组仅用低分子右旋糖酐-40治疗。低分子右旋糖酐-40和己酮可可碱联合治疗时，血液流变学特性的改善具有统计学意义。根据这一流变学结果，对两组突发性耳聋患者（一组为选定患者，一组为非选定患者）用己酮可可碱和低分子右旋糖酐40治疗后的听力改善情况进行了评估，并与韦瑙格1984年给出的自然缓解率进行了比较。
