Shen Lin, Wei Chuanchuan, Yang Wenli, Xiong Ying, Li Yifan, Li Dongjun, Wang Ziyang, Chen Wei, Zhao Qi, Li Yifeng, Cui Rui, Liu Qian
Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing, 100730, China.
Int Ophthalmol. 2023 Dec;43(12):4911-4919. doi: 10.1007/s10792-023-02894-w. Epub 2023 Oct 13.
To investigate the relationship between lens morphology and aberrations in patients with myopia.
This cross-sectional study included 155 patients with myopia in their right eyes. Spherical power and cylindrical power were achieved by cycloplegic autorefraction. The eyes were divided into three groups for analysis based on their spherical equivalent (SE) values. The 4 mm and 6 mm ocular and internal aberrations were measured using the OPD-scan III. Lens parameters were measured using CASIA2, including lens thickness (LT), radius of anterior/posterior lens surface curvature (RAL/RPL), lens decentration (DEC), and lens tilt (TILT). The differences of lenticular parameters and aberration parameters among the three groups analyzed with ANOVA or Kruskal Wallis test. Pearson correlation or Spearman correlation analysis was performed to evaluate the relationships between the lens parameters and aberrations. A p value < 0.05 indicated statistical significance.
The difference in LT, RAL, DEC and TITL among the three groups was statistically significant (p < 0.05). And there were differences among differences in internal high-order aberrations, spherical aberration, and coma aberration(p < 0.05).Spherical power was positively correlated with LT and TITL (p < 0.05) and negatively correlated with DEC, RAL, and RPL (p < 0.05). Cylindrical power was positively correlated with LT (p < 0.05) and negatively correlated DEC (p < 0.05); The lenticular parameters (LT, RAL, DEC, and TILT) were mainly correlated with the ocular and internal spherical aberration. LT and DEC were correlated with ocular and internal higher-order aberrations and coma aberration.
DEC and LT were the main factors affecting aberrations in patients with myopia.
探讨近视患者晶状体形态与像差之间的关系。
这项横断面研究纳入了155例右眼近视患者。通过睫状肌麻痹自动验光获得球镜度数和柱镜度数。根据等效球镜（SE）值将眼睛分为三组进行分析。使用OPD-scan III测量4毫米和6毫米的眼内像差和内部像差。使用CASIA2测量晶状体参数，包括晶状体厚度（LT）、晶状体前/后表面曲率半径（RAL/RPL）、晶状体偏心（DEC）和晶状体倾斜（TILT）。用方差分析或Kruskal Wallis检验分析三组之间晶状体参数和像差参数的差异。进行Pearson相关或Spearman相关分析以评估晶状体参数与像差之间的关系。p值<0.05表示具有统计学意义。
三组之间的LT、RAL、DEC和TITL差异具有统计学意义（p<0.05）。并且内部高阶像差、球差和彗差的差异也存在差异（p<0.05）。球镜度数与LT和TITL呈正相关（p<0.05），与DEC、RAL和RPL呈负相关（p<0.05）。柱镜度数与LT呈正相关（p<0.05），与DEC呈负相关（p<0.05）；晶状体参数（LT、RAL、DEC和TILT）主要与眼内和内部球差相关。LT和DEC与眼内和内部高阶像差及彗差相关。
DEC和LT是影响近视患者像差的主要因素。
